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属:生物活性代谢物的丰富来源。

Genus: A Rich Source of Bioactive Metabolites.

作者信息

Pinto Diana C G A, Rahmouni Naima, Beghidja Noureddine, Silva Artur M S

机构信息

Department of Chemistry and QOPNA, University of Aveiro, Campus de Santiago, 3810193 Aveiro, Portugal.

Unité de Recherche et Valorisation des Ressources Naturelles, Molécules Bioactives et Analyse Physico-Chimiques et Biologiques, Université des Frères Mentouri Constantine 1, Constantine, Algérie.

出版信息

Medicines (Basel). 2018 Oct 9;5(4):110. doi: 10.3390/medicines5040110.

DOI:10.3390/medicines5040110
PMID:30304864
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6313729/
Abstract

The genus (family Caprifoliaceae) is considered large (618 scientific plant names of species) although only 62 have accepted Latin binominal names. The majority of the species are widely distributed in the Mediterranean region and some species are used in traditional medicine systems. For instance, L. is used traditionally against diphtheria while Fisch. Ex Roem. and Schult. is used in Mongolian and Tibetan traditional medical settings to treat liver diseases. The richness of species in secondary metabolites such as iridoids, flavonoids and pentacyclic triterpenoids may contribute to its use in folk medicine. Details on the most recent and relevant pharmacological in vivo studies on the bioactive secondary metabolites isolated from species will be summarized and thoroughly discussed.

摘要

忍冬属(忍冬科)被认为种类繁多(有618个科学的植物物种名称),尽管只有62个具有公认的拉丁双名法名称。大多数忍冬属物种广泛分布于地中海地区,一些忍冬属物种被用于传统医学体系。例如,传统上用忍冬来对抗白喉,而蒙古黄芪(Fisch. Ex Roem. and Schult.)在蒙古和藏医传统医疗中用于治疗肝脏疾病。忍冬属物种在次生代谢产物如环烯醚萜、黄酮类化合物和五环三萜类化合物方面的丰富性可能有助于其在民间医学中的应用。将总结并深入讨论从忍冬属物种中分离出的生物活性次生代谢产物的最新及相关体内药理学研究细节。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7b4/6313729/f683fb906018/medicines-05-00110-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7b4/6313729/763353ed298f/medicines-05-00110-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7b4/6313729/a7781658eb1d/medicines-05-00110-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7b4/6313729/d27299bb380e/medicines-05-00110-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7b4/6313729/f683fb906018/medicines-05-00110-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7b4/6313729/763353ed298f/medicines-05-00110-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7b4/6313729/a7781658eb1d/medicines-05-00110-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7b4/6313729/d27299bb380e/medicines-05-00110-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7b4/6313729/f683fb906018/medicines-05-00110-g004.jpg

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