Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, T6G2P5, Canada.
FEMS Microbiol Ecol. 2019 Jan 1;95(1). doi: 10.1093/femsec/fiy203.
This study evaluated the effect of feeding non-heated and heated colostrum on the mucosa- and digesta-associated microbiota in the colon of dairy calves during the first 12 h of life. Thirty-two neonatal Holstein male calves were fed: no colostrum (NC, n = 8), non-heated colostrum (FC, n = 12) and heated colostrum (HC (60 °C, 60 min), n = 12) immediately after birth. The abundances of mucosa- and digesta-associated total bacteria were higher in the colon of FC fed calves compared to those fed no colostrum (NC) at 12 h of life. Compare to NC calves, a higher proportion of mucosa- and digesta-associated Clostridium cluster XIVa and Bifidobacterium, and a lower abundance of mucosa and digesta-associated E. coli were detected in the colon of FC and HC fed calves, as well as a tentatively lower relative abundance of Escherichia-Shigella genus in colon mucosa of HC fed calves. In addition, HC calves had lower abundances of E. coli and higher abundances of Bifidobacterium in mucosa-associated microbiota than FC fed calves. Our results suggest that feeding non-heated colostrum immediately after birth benefit neonatal calves with increased Bifidobacterium and decreased opportunistic pathogenic E. coli and Escherichia-Shigella genus in the colon, and feeding heated colostrum can fortify such effects.
本研究评估了在生命的头 12 小时内，给新生荷斯坦公犊饲喂未加热和加热的初乳对其结肠黏膜和食糜相关微生物群的影响。32 头新生雄性荷斯坦公犊分别饲喂：无初乳（NC，n = 8）、未加热初乳（FC，n = 12）和加热初乳（HC（60°C，60min），n = 12）。与出生后不饲喂初乳（NC）的犊牛相比，饲喂 FC 的犊牛在生命 12 小时时结肠黏膜和食糜相关总细菌的丰度更高。与 NC 犊牛相比，FC 和 HC 饲喂的犊牛结肠中黏膜和食糜相关的 Clostridium cluster XIVa 和双歧杆菌比例更高，而黏膜和食糜相关的大肠杆菌丰度更低，以及 HC 饲喂的犊牛结肠黏膜中 Escherichia-Shigella 属的相对丰度也更低。此外，与 FC 饲喂的犊牛相比，HC 饲喂的犊牛结肠黏膜相关微生物群中大肠杆菌丰度更低，双歧杆菌丰度更高。我们的研究结果表明，出生后立即饲喂未加热的初乳有利于新生犊牛增加双歧杆菌和减少机会性致病性大肠杆菌和 Escherichia-Shigella 属，而饲喂加热的初乳可以增强这种效果。
