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用于治疗压疮的支撑面。

Support surfaces for treating pressure ulcers.

作者信息

McInnes Elizabeth, Jammali-Blasi Asmara, Bell-Syer Sally Em, Leung Vannessa

机构信息

Nursing Research Institute, St Vincent's Health Australia (Sydney) and Australian Catholic University (ACU), School of Nursing, Midwifery and Paramedicine, Australian Catholic University, Executive Suite, Level 5 DeLacy Building, St Vincent's Hospital, 390 Victoria Road, Darlinghurst, New South Wales, Australia, 2010.

出版信息

Cochrane Database Syst Rev. 2018 Oct 11;10(10):CD009490. doi: 10.1002/14651858.CD009490.pub2.

DOI:10.1002/14651858.CD009490.pub2
PMID:30307602
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6517160/
Abstract

BACKGROUND

Pressure ulcers are treated by reducing pressure on the areas of damaged skin. Special support surfaces (including beds, mattresses and cushions) designed to redistribute pressure, are widely used as treatments. The relative effects of different support surfaces are unclear. This is an update of an existing review.

OBJECTIVES

To assess the effects of pressure-relieving support surfaces in the treatment of pressure ulcers.

SEARCH METHODS

In September 2017 we searched the Cochrane Wounds Specialised Register; the Cochrane Central Register of Controlled Trials (CENTRAL); Ovid MEDLINE (including In-Process & Other Non-Indexed Citations); Ovid Embase and EBSCO CINAHL Plus. We also searched clinical trials registries for ongoing and unpublished studies, and scanned reference lists of relevant included studies as well as reviews, meta-analyses and health technology reports to identify additional studies. There were no restrictions with respect to language, date of publication or study setting.

SELECTION CRITERIA

We included published or unpublished randomised controlled trials (RCTs), that assessed the effects of support surfaces for treating pressure ulcers, in any participant group or setting.

DATA COLLECTION AND ANALYSIS

Data extraction, assessment of 'Risk of bias' and GRADE assessments were performed independently by two review authors. Trials with similar participants, comparisons and outcomes were considered for meta-analysis. Where meta-analysis was inappropriate, we reported the results of the trials narratively. Where possible, we planned to report data as either risk ratio or mean difference as appropriate.

MAIN RESULTS

For this update we identified one new trial of support surfaces for pressure ulcer treatment, bringing the total to 19 trials involving 3241 participants. Most trials were small, with sample sizes ranging from 20 to 1971, and were generally at high or unclear risk of bias.

PRIMARY OUTCOME

healing of existing pressure ulcersLow-tech constant pressure support surfacesIt is uncertain whether profiling beds increase the proportion of pressure ulcer which heal compared with standard hospital beds as the evidence is of very low certainty: (RR 3.96, 95% CI 1.28 to 12.24), downgraded for serious risk of bias, serious imprecision and indirectness (1 study; 70 participants).There is currently no clear difference in ulcer healing between water-filled support surfaces and foam replacement mattresses: (RR 0.93, 95% CI 0.63 to 1.37); low-certainty evidence downgraded for serious risk of bias and serious imprecision (1 study; 120 participants).Further analysis could not be performed for polyester overlays versus gel overlays (1 study; 72 participants), non-powered mattresses versus low-air-loss mattresses (1 study; 20 participants) or standard hospital mattresses with sheepskin overlays versus standard hospital mattresses (1 study; 36 participants).High-tech pressure support surfacesIt is currently unclear whether high-tech pressure support surfaces (such as low-air-loss beds, air suspension beds, and alternating pressure surfaces) improve the healing of pressure ulcers (14 studies; 2923 participants) or which intervention may be more effective. The certainty of the evidence is generally low, downgraded mostly for risk of bias, indirectness and imprecision.Secondary outcomesNo analyses were undertaken with respect to secondary outcomes including participant comfort and surface reliability and acceptability as reporting of these within the included trials was very limited.Overall, the evidence is of low to very low certainty and was primarily downgraded due to risk of bias and imprecision with some indirectness.

AUTHORS' CONCLUSIONS: Based on the current evidence, it is unclear whether any particular type of low- or high-tech support surface is more effective at healing pressure ulcers than standard support surfaces.

摘要

背景

压疮的治疗方法是减轻受损皮肤区域的压力。旨在重新分配压力的特殊支撑面(包括床、床垫和靠垫)被广泛用作治疗手段。不同支撑面的相对效果尚不清楚。这是对现有综述的更新。

目的

评估减压支撑面在治疗压疮中的效果。

检索方法

2017年9月,我们检索了Cochrane伤口专业注册库、Cochrane对照试验中心注册库(CENTRAL)、Ovid MEDLINE(包括在研及其他未索引的文献)、Ovid Embase和EBSCO CINAHL Plus。我们还检索了临床试验注册库以查找正在进行和未发表的研究,并浏览了相关纳入研究以及综述、荟萃分析和卫生技术报告的参考文献列表以识别其他研究。在语言、出版日期或研究环境方面没有限制。

选择标准

我们纳入已发表或未发表的随机对照试验(RCT),这些试验评估了支撑面在任何参与者群体或环境中治疗压疮的效果。

数据收集与分析

数据提取、“偏倚风险”评估和GRADE评估由两位综述作者独立进行。考虑对具有相似参与者、对照和结局的试验进行荟萃分析。在荟萃分析不适用的情况下,我们以叙述方式报告试验结果。在可能的情况下,我们计划根据情况将数据报告为风险比或均值差。

主要结果

对于本次更新,我们识别出一项关于压疮治疗支撑面的新试验,使试验总数达到19项,涉及3241名参与者。大多数试验规模较小,样本量从20到1971不等,且总体偏倚风险较高或不明确。

主要结局

现有压疮的愈合

低技术恒压支撑面

与标准医院病床相比,轮廓床是否能增加压疮愈合的比例尚不确定,因为证据的确定性非常低:(风险比3.96,95%置信区间1.28至12.24),因存在严重偏倚风险、严重不精确性和间接性而降级(1项研究;70名参与者)。

目前,充水支撑面和泡沫替代床垫在溃疡愈合方面没有明显差异:(风险比0.93,95%置信区间0.63至1.37);低确定性证据因存在严重偏倚风险和严重不精确性而降级(1项研究;120名参与者)。

对于聚酯覆盖物与凝胶覆盖物(1项研究;72名参与者)、无动力床垫与低空气丧失床垫(1项研究;20名参与者)或带羊皮覆盖物的标准医院床垫与标准医院床垫(1项研究;36名参与者),无法进行进一步分析。

高技术压力支撑面

目前尚不清楚高技术压力支撑面(如低空气丧失床、空气悬浮床和交替压力面)是否能改善压疮的愈合情况(14项研究;2923名参与者),也不清楚哪种干预措施可能更有效。证据的确定性总体较低,主要因偏倚风险、间接性和不精确性而降级。

次要结局

未对次要结局进行分析,包括参与者舒适度、支撑面可靠性和可接受性,因为纳入试验中对这些方面的报告非常有限。

总体而言,证据的确定性为低到非常低,主要因偏倚风险、不精确性以及一些间接性而降级。

作者结论

基于目前的证据,尚不清楚任何特定类型的低技术或高技术支撑面在愈合压疮方面是否比标准支撑面更有效。

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本文引用的文献

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Foam dressings for treating pressure ulcers.用于治疗压疮的泡沫敷料。
Cochrane Database Syst Rev. 2017 Oct 12;10(10):CD011332. doi: 10.1002/14651858.CD011332.pub2.
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The Efficacy of a Viscoelastic Foam Overlay on Prevention of Pressure Injury in Acutely Ill Patients: A Prospective Randomized Controlled Trial.一种粘弹性泡沫敷料预防急性病患者压力性损伤的疗效:一项前瞻性随机对照试验。
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Dressings and topical agents for treating pressure ulcers.用于治疗压疮的敷料和外用剂。
Cochrane Database Syst Rev. 2017 Jun 22;6(6):CD011947. doi: 10.1002/14651858.CD011947.pub2.
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Anabolic steroids for treating pressure ulcers.用于治疗压疮的合成代谢类固醇。
Cochrane Database Syst Rev. 2017 Jun 20;6(6):CD011375. doi: 10.1002/14651858.CD011375.pub2.
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Pressure ulcers prevention efficacy of an alternating pressure air mattress in elderly patients: E²MAO a randomised study.交替压力气垫床对老年患者压疮的预防效果:E²MAO随机研究
J Wound Care. 2017 Jun 2;26(6):304-312. doi: 10.12968/jowc.2017.26.6.304.
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Therapeutic ultrasound for venous leg ulcers.用于腿部静脉溃疡的治疗性超声
Cochrane Database Syst Rev. 2017 May 15;5(5):CD001180. doi: 10.1002/14651858.CD001180.pub4.
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Pressure RElieving Support SUrfaces: a Randomised Evaluation 2 (PRESSURE 2) photographic validation sub-study: study protocol for a randomised controlled trial.减压支撑表面:随机评估2(PRESSURE 2)照片验证子研究:一项随机对照试验的研究方案
Trials. 2017 Mar 20;18(1):132. doi: 10.1186/s13063-017-1851-5.
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Pressure RElieving Support SUrfaces: a Randomised Evaluation 2 (PRESSURE 2): study protocol for a randomised controlled trial.压力缓解支撑面:随机评估2(PRESSURE 2):一项随机对照试验的研究方案
Trials. 2016 Dec 20;17(1):604. doi: 10.1186/s13063-016-1703-8.
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The cost of pressure area management in an intensive care unit.重症监护病房压力性损伤管理的成本
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Bed rest for pressure ulcer healing in wheelchair users.卧床休息对轮椅使用者压疮愈合的作用
Cochrane Database Syst Rev. 2016 Oct 17;10(10):CD011999. doi: 10.1002/14651858.CD011999.pub2.