Evidence for a T-cell reaction in the cutaneous sarcoid granuloma.

In cutaneous sarcoidosis, mononuclear cells of granuloma have been freed and characterized by immunological tests. Of these cells, 84% of them were found to be T dependent by the E rosette test. A similar value (79%) was obtained in the stroma of delayed hypersensitivity reaction, whose immunological functions are well known. However, the physiological role of the thymus dependent pupulation within granulomas must be established.