USDA APHIS Wildlife Services, NWRC, Fort Collins, Colorado, United States of America.
Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, United States of America.
PLoS Negl Trop Dis. 2018 Oct 11;12(10):e0006866. doi: 10.1371/journal.pntd.0006866. eCollection 2018 Oct.
The global economic impact of canine rabies has been estimated by several studies. Asia bears a disproportionate burden of this zoonosis due to high levels of human deaths and rates of post-exposure prophylaxis (PEP), but low investment in preventative dog vaccination. The same factors that cause rabies to burden much of Asia are also present in Viet Nam. This study estimated the economic burden of canine rabies in a societal perspective including direct and indirect cost of rabies in dogs, livestock, and humans. Using data collected from personal interviews, published literature, published and supplementary reports, and primary data collection, we estimated the economic impact of canine rabies in Viet Nam over a ten year period (2005-2014). We incorporated the direct and indirect costs for PEP, dog vaccination efforts, livestock losses, and disability adjusted life years (DALYs) into the analysis. General findings from this analysis indicated that over the 10 year study period, the total economic impact of canine rabies was over $719 million USD. The largest portion of impacts (92%) were made up of PEP-related costs. Canine rabies created between 36,560 and 45,700 DALYs, measured in years of life lost (YLL). A total of 914 human deaths were reported over the study period. Deaths/100,000 people were 0.11, which is lower than the reported level for Asian countries. The cost per dog vaccinated was $1.75 USD. Our results indicate that canine rabies impacts in Viet Nam are consistent with the burden elsewhere reported in Asia, with large expenditures on PEP and very small investments in dog vaccination.
几项研究估计了犬狂犬病的全球经济影响。由于人类死亡人数和接触后预防(PEP)率高,但对预防犬只接种疫苗的投资低,亚洲承担了这种人畜共患病的不成比例的负担。导致狂犬病给亚洲大部分地区带来负担的同样因素也存在于越南。本研究从社会角度估算了犬狂犬病的经济负担,包括狗、牲畜和人类狂犬病的直接和间接成本。我们使用个人访谈、已发表的文献、已发表和补充报告以及初级数据收集所收集的数据,估算了越南在十年期间(2005-2014 年)犬狂犬病的经济影响。我们将 PEP、犬只疫苗接种工作、牲畜损失和残疾调整生命年(DALY)的直接和间接成本纳入分析。该分析的一般结论表明,在 10 年的研究期间,犬狂犬病的总经济影响超过 7.19 亿美元。影响的最大部分(92%)由 PEP 相关费用构成。犬狂犬病造成 36560 至 45700 个 DALY,以生命年损失(YLL)衡量。在研究期间共报告了 914 例人类死亡。每 10 万人死亡/死亡人数为 0.11,低于亚洲国家报告的水平。每只接种疫苗的狗的费用为 1.75 美元。我们的研究结果表明,越南的犬狂犬病影响与亚洲其他地区报告的负担一致,PEP 支出巨大,而犬只接种疫苗的投资非常小。