Ran Xuhua, Cheng Jiajia, Wang Miaomiao, Chen Xiaohong, Wang Haoxian, Ge Yu, Ni Hongbo, Zhang Xiao-Xuan, Wen Xiaobo
College of Animal Science & Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang Province 163319, China.
College of Animal Science & Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang Province 163319, China.
Acta Trop. 2019 Jan;189:117-123. doi: 10.1016/j.actatropica.2018.10.002. Epub 2018 Oct 9.
Brucellosis remains one of the most common zoonotic diseases globally with more than a half million human cases reported annually. The Brucella reservoir associated with livestock brucellosis poses a significant threat to public health, and awareness of the seroprevalence and spatial distribution of livestock brucellosis is valuable for the prevention and control of diseases caused by Brucella, especially human brucellosis. Therefore, we conducted a systematic review and meta-analysis to evaluate the seroprevalence of brucellosis in dairy cattle in China. We retrieved 88 studies related to the seroprevalence of brucellosis in dairy cattle in China in which samples were harvested between 2008 and 2018. The results of our systematic review and meta-analysis reveal that the overall seroprevalence of brucellosis in dairy cattle herds in China was 1.9% during the selected period, rising from 1.6% in 2008-2012 to 2.6% in 2013-2018. In Northern China, where the traditional agropastoral areas with more developed animal breeding industry are located, the brucellosis seroprevalence was >10%. In contrast, the seroprevalence of brucellosis in Southern China reached only 5.5%. At the provincial level, the highest brucellosis seroprevalence in dairy cattle was estimated at >30% in Jilin province, followed by Shanxi, Ningxia, Inner Mongolia, and Guizhou, each with a prevalence of 10-20%. Additionally, the seroprevalence of brucellosis in some local areas was >30% or even >50%, indicating that Brucella infection was highly endemic in dairy herds in China. Our data may facilitate the prevention and control of brucellosis in domestic animals in China. Further epidemiological surveillance and the administration of a comprehensive monitoring program to determine the risk factors associated with brucellosis incidence in humans and domestic animals are recommended to refine brucellosis control strategies.
布鲁氏菌病仍然是全球最常见的人畜共患病之一，每年报告的人类病例超过50万例。与家畜布鲁氏菌病相关的布鲁氏菌宿主对公众健康构成重大威胁，了解家畜布鲁氏菌病的血清流行率和空间分布对于预防和控制由布鲁氏菌引起的疾病，尤其是人类布鲁氏菌病具有重要价值。因此，我们进行了一项系统评价和荟萃分析，以评估中国奶牛布鲁氏菌病的血清流行率。我们检索了88项与2008年至2018年期间采集样本的中国奶牛布鲁氏菌病血清流行率相关的研究。我们的系统评价和荟萃分析结果显示，在选定时期内，中国奶牛群中布鲁氏菌病的总体血清流行率为1.9%，从2008 - 2012年的1.6%上升至2013 - 2018年的2.6%。在中国北方，传统农牧区的畜牧业较为发达，布鲁氏菌病血清流行率>10%。相比之下，中国南方的布鲁氏菌病血清流行率仅为5.5%。在省级层面，吉林省奶牛布鲁氏菌病血清流行率估计最高，>30%，其次是山西、宁夏、内蒙古和贵州，患病率均为10% - 20%。此外，一些局部地区的布鲁氏菌病血清流行率>30%，甚至>50%，表明布鲁氏菌感染在中国奶牛群中高度流行。我们的数据可能有助于中国家畜布鲁氏菌病的预防和控制。建议进一步开展流行病学监测，并实施全面监测计划以确定与人类和家畜布鲁氏菌病发病率相关的风险因素，从而完善布鲁氏菌病控制策略。
