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香料精油的抗菌活性及其对人体病原菌成熟生物膜的作用。

Antimicrobial activity of spices essential oils and its effectiveness on mature biofilms of human pathogens.

机构信息

Department of Life Science, University of Modena and Reggio Emilia, Modena, Italy.

出版信息

Nat Prod Res. 2020 Feb;34(4):567-574. doi: 10.1080/14786419.2018.1490904. Epub 2018 Oct 13.

Abstract

The antibacterial activity of L., , , and L. essential oils (EOs) against some common pathogenic microorganisms ( ATCC 6538, ATCC 14990, ATCC 29212, ATCC 1915, ATCC 8739, ATCC 27853, ATCC 7966, ATCC 10005, ATCC 13883, and ATCC 10231) and their biofilms was studied. The EOs inhibitory effects were evaluated by both Agar Well Diffusion assay and Minimum Inhibitory Concentration (MIC) determination. The most active EOs, cinnamon and cloves, were also tested on 18, 24, 48, 72 hours mature biofilms. Cinnamon and cloves exhibited the best results showing a significant activity against all the tested bacteria. Concerning biofilm, results suggest that oil may be a useful approach to impair the biofilm produced by the tested Gram-negative bacteria. [Formula: see text].

摘要

研究了肉桂、丁香、芫荽和罗勒精油(EOs)对一些常见的致病性微生物(ATCC 6538、ATCC 14990、ATCC 29212、ATCC 1915、ATCC 8739、ATCC 27853、ATCC 7966、ATCC 10005、ATCC 13883 和 ATCC 10231)及其生物膜的抗菌活性。通过琼脂孔扩散试验和最小抑菌浓度(MIC)测定评估了 EOs 的抑制作用。最有效的 EOs,肉桂和丁香,也在 18、24、48 和 72 小时成熟生物膜上进行了测试。肉桂和丁香对所有测试的细菌都表现出了显著的活性。关于生物膜,结果表明,[化学式:见正文]油可能是一种有用的方法来削弱测试的革兰氏阴性细菌产生的生物膜。

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