用于诊断人工膝关节感染的术前抽吸培养（PAC）
Preoperative Aspiration Culture (PAC) for the Diagnosis of Infection in a Prosthetic Knee Joint.
作者信息
Rodriguez-Merchan E Carlos
机构信息
Research performed at the Department of Orthopaedic Surgery, La Paz University Hospital, Madrid, Spain.
Department of Orthopaedic Surgery, La Paz University Hospital-IdiPaz, Paseo de la Castellana, Madrid, Spain.
出版信息
Arch Bone Jt Surg. 2018 Sep;6(5):342-345.
Abstract
BACKGROUND
Periprosthetic infection is the most serious joint replacement complication, occurring in 0.8-1.9% of total knee arthroplasties (TKAs).This review aims to define the role of preoperative aspiration culture (PAC) for diagnosis of TKA infection.
METHODS
A PubMed (MEDLINE) search related to TKA infection and PAC was analyzed. The main criteria for selection were that the articles were focused in the aforementioned question.
RESULTS
Twenty articles were found, but only fourteen were selected and reviewed because they were deeply focused on the topic. PAC has shown an average sensitivity of 67.6% (range, 28% to 100%) and an average specificity of 98.4% (range, 96% to 100%).
CONCLUSION
PAC has moderate to high sensitivity and very high specificity for diagnosing TKA infection.
摘要
背景
假体周围感染是最严重的关节置换并发症，全膝关节置换术（TKA）中发生率为0.8%-1.9%。本综述旨在明确术前抽吸培养（PAC）在TKA感染诊断中的作用。
方法
分析了PubMed（MEDLINE）中与TKA感染和PAC相关的搜索结果。主要入选标准是文章聚焦于上述问题。
结果
共找到20篇文章，但仅14篇被选中并进行综述，因为它们深度聚焦于该主题。PAC的平均敏感性为67.6%（范围28%至100%），平均特异性为98.4%（范围96%至100%）。
结论
PAC对TKA感染的诊断具有中度至高敏感性和非常高的特异性。
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