Siemens Healthcare GmbH, Erlangen, Germany.
Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Magn Reson Med. 2019 Apr;81(4):2347-2359. doi: 10.1002/mrm.27558. Epub 2018 Oct 15.
To develop and evaluate the magnetic resonance field fingerprinting method that simultaneously generates T , T , B , and maps from a single continuous measurement.
An encoding pattern was designed to integrate true fast imaging with steady-state precession (TrueFISP), fast imaging with steady-state precession (FISP), and fast low-angle shot (FLASH) sequence segments with varying flip angles, radio frequency (RF) phases, TEs, and gradient moments in a continuous acquisition. A multistep matching process was introduced that includes steps for integrated spiral deblurring and the correction of intravoxel phase dispersion. The method was evaluated in phantoms as well as in vivo studies in brain and lower abdomen.
Simultaneous measurement of T , T , B , and is achieved with T and T subsequently being less afflicted by B and variations. Phantom results demonstrate the stability of generated parameter maps. Higher undersampling factors and spatial resolution can be achieved with the proposed method as compared with solely FISP-based magnetic resonance fingerprinting. High-resolution B maps can potentially be further used as diagnostic information.
The proposed magnetic resonance field fingerprinting method can estimate T , T , B , and maps accurately in phantoms, in the brain, and in the lower abdomen.
开发并评估一种磁共振磁场指纹识别方法，该方法能够从单次连续测量中同时生成 T1、T2、B 和 图。
设计了一种编码模式，将真正的快速成像与稳态进动（TrueFISP）、快速成像与稳态进动（FISP）以及快速低角度激发（FLASH）序列段与不同的翻转角、射频（RF）相位、TE 和梯度矩集成在连续采集过程中。引入了一个多步骤匹配过程，包括集成螺旋去模糊和纠正体素内相位弥散的步骤。该方法在体模以及脑部和下腹部的活体研究中进行了评估。
实现了 T1、T2、B 和 的同时测量，并且 T1 和 T2 随后受到 B 和 的变化的影响较小。体模结果表明生成的参数图具有稳定性。与仅基于 FISP 的磁共振指纹识别方法相比，该方法可以实现更高的欠采样因子和空间分辨率。高分辨率的 B 图有可能进一步用作诊断信息。
所提出的磁共振磁场指纹识别方法能够在体模、脑部和下腹部准确估计 T1、T2、B 和 图。
