• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Genomic Characterization of Carbapenemase-Producing Klebsiella pneumoniae with Chromosomally Carried .产碳青霉烯酶肺炎克雷伯菌的染色体携带. 基因的基因组特征
Antimicrob Agents Chemother. 2018 Nov 26;62(12). doi: 10.1128/AAC.01520-18. Print 2018 Dec.
2
Genome sequencing of an extended series of NDM-producing Klebsiella pneumoniae isolates from neonatal infections in a Nepali hospital characterizes the extent of community- versus hospital-associated transmission in an endemic setting.对尼泊尔一家医院新生儿感染中一系列产NDM肺炎克雷伯菌分离株进行的全基因组测序，确定了在地方流行环境中社区传播与医院相关传播的程度。
Antimicrob Agents Chemother. 2014 Dec;58(12):7347-57. doi: 10.1128/AAC.03900-14. Epub 2014 Sep 29.
3
Genetic organization of transposase regions surrounding blaKPC carbapenemase genes on plasmids from Klebsiella strains isolated in a New York City hospital.从纽约市一家医院分离出的克雷伯氏菌菌株质粒上 blaKPC 碳青霉烯酶基因周围转座酶区域的基因组织。
Antimicrob Agents Chemother. 2009 May;53(5):1998-2004. doi: 10.1128/AAC.01355-08. Epub 2009 Mar 2.
4
Emergence of Multidrug-Resistant New Delhi Metallo-β-Lactamase-1-Producing Klebsiella pneumoniae in Egypt.埃及产新型耐多药新德里金属β-内酰胺酶-1肺炎克雷伯菌的出现。
Microb Drug Resist. 2017 Jun;23(4):480-487. doi: 10.1089/mdr.2016.0003. Epub 2016 Aug 30.
5
Chromosomal Integration of the Klebsiella pneumoniae Carbapenemase Gene, , in Klebsiella Species Is Elusive but Not Rare.肺炎克雷伯菌碳青霉烯酶基因在克雷伯菌属中的染色体整合难以捉摸但并不罕见。
Antimicrob Agents Chemother. 2017 Feb 23;61(3). doi: 10.1128/AAC.01823-16. Print 2017 Mar.
6
Emergence of Klebsiella pneumoniae ST273 Carrying bla and ST656 Carrying bla in Manila, Philippines.菲律宾马尼拉出现携带bla的肺炎克雷伯菌ST273和携带bla的ST656。
Microb Drug Resist. 2016 Oct;22(7):585-588. doi: 10.1089/mdr.2015.0205. Epub 2016 Mar 31.
7
Rapid Increase in Carbapenemase-Producing Enterobacteriaceae in Retail Meat Driven by the Spread of the -Carrying IncX3 Plasmid in China from 2016 to 2018.2016 年至 2018 年，中国携带 - 碳青霉烯酶基因 IncX3 质粒的碳青霉烯酶产生肠杆菌科在零售肉中的快速传播。
Antimicrob Agents Chemother. 2019 Jul 25;63(8). doi: 10.1128/AAC.00573-19. Print 2019 Aug.
8
Molecular characterization of carbapenem-resistant strains of Klebsiella pneumoniae isolated from Iranian patients: first identification of blaKPC gene in Iran.从伊朗患者中分离出的耐碳青霉烯肺炎克雷伯菌菌株的分子特征：伊朗首次鉴定出blaKPC基因
Microb Drug Resist. 2014 Aug;20(4):285-93. doi: 10.1089/mdr.2013.0074. Epub 2014 Jan 15.
9
Outbreak of plasmid-mediated NDM-1-producing Klebsiella pneumoniae ST105 among neonatal patients in Yunnan, China.中国云南新生儿患者中质粒介导产NDM-1肺炎克雷伯菌ST105的暴发。
Ann Clin Microbiol Antimicrob. 2016 Feb 19;15:10. doi: 10.1186/s12941-016-0124-6.
10
Rapid expansion of KPC-2-producing Klebsiella pneumoniae isolates in two Texas hospitals due to clonal spread of ST258 and ST307 lineages.由于 ST258 和 ST307 谱系的克隆传播，导致两所德克萨斯州医院中产 KPC-2 的肺炎克雷伯菌分离株迅速扩张。
Microb Drug Resist. 2013 Aug;19(4):295-7. doi: 10.1089/mdr.2012.0238. Epub 2013 Mar 26.

引用本文的文献

1
Genetic characteristics of chromosomally integrated carbapenemase gene (bla) in isolates of Proteus mirabilis.奇异变形杆菌染色体整合碳青霉烯酶基因（bla）的遗传特征。
BMC Microbiol. 2024 Jun 19;24(1):216. doi: 10.1186/s12866-024-03365-7.
2
Regional dissemination of NDM-1 producing ST1740, with a subset of strains co-producing VIM-4 or IMP-13, France, 2019 to 2022.2019 年至 2022 年期间，法国出现了携带 NDM-1 的 ST1740 型菌株的区域性传播，其中一部分菌株还同时产生 VIM-4 或 IMP-13。
Euro Surveill. 2024 Mar;29(11). doi: 10.2807/1560-7917.ES.2024.29.11.2300521.
3
Whole-Genome Sequencing Revealed the Fusion Plasmids Capable of Transmission and Acquisition of Both Antimicrobial Resistance and Hypervirulence Determinants in Multidrug-Resistant Isolates.全基因组测序揭示了在多重耐药菌株中能够传递和获得抗微生物耐药性及高毒力决定因素的融合质粒。
Microorganisms. 2023 May 17;11(5):1314. doi: 10.3390/microorganisms11051314.
4
Carbapenem triggers dissemination of chromosomally integrated carbapenemase genes via conjugative plasmids in .碳青霉烯类抗生素通过可接合质粒触发染色体整合碳青霉烯酶基因的传播。
mSystems. 2023 Jun 29;8(3):e0127522. doi: 10.1128/msystems.01275-22. Epub 2023 Jun 5.
5
NDM-5-carrying ST437 belonging to high-risk clonal complex (CC11) from an urban river in eastern India.来自印度东部一条城市河流的、携带NDM-5的ST437，属于高危克隆复合体（CC11）。
3 Biotech. 2023 May;13(5):139. doi: 10.1007/s13205-023-03556-5. Epub 2023 Apr 26.
6
A Nationwide Plasmidome Surveillance in Thailand Reveals a Limited Variety of New Delhi Metallo-β-Lactamase-Producing Carbapenem-Resistant Clones and Spreading Plasmids.泰国全国范围的质粒组监测揭示了有限数量的新德里金属β-内酰胺酶产生碳青霉烯类耐药克隆和传播质粒。
J Clin Microbiol. 2022 Dec 21;60(12):e0108022. doi: 10.1128/jcm.01080-22. Epub 2022 Nov 29.
7
Role of Chromosome- and/or Plasmid-Located on the Carbapenem Resistance and the Gene Stability in Escherichia coli.染色体和/或质粒定位在大肠埃希菌碳青霉烯类耐药性和基因稳定性中的作用。
Microbiol Spectr. 2022 Aug 31;10(4):e0058722. doi: 10.1128/spectrum.00587-22. Epub 2022 Aug 2.
8
Spread of Carbapenem-Resistant Klebsiella pneumoniae Clinical Isolates Producing NDM-Type Metallo-β-Lactamase in Myanmar.缅甸产 NDM 型金属β-内酰胺酶的耐碳青霉烯类肺炎克雷伯菌临床分离株的传播。
Microbiol Spectr. 2022 Aug 31;10(4):e0067322. doi: 10.1128/spectrum.00673-22. Epub 2022 Jun 28.
9
Emergence of -Carrying K433 Isolated From Patient With Community-Acquired Pneumonia.从社区获得性肺炎患者中分离出携带K433的菌株。
Front Microbiol. 2022 May 19;13:825389. doi: 10.3389/fmicb.2022.825389. eCollection 2022.
10
Characterization of an Extensively Drug-Resistant Serovar Indiana Strain Harboring Chromosomal in China.中国一株携带染色体的广泛耐药印第安纳血清型菌株的特征分析。
Infect Drug Resist. 2022 Apr 20;15:2015-2019. doi: 10.2147/IDR.S364115. eCollection 2022.

本文引用的文献

1
Emergence and Evolution of Multidrug-Resistant Klebsiella pneumoniae with both and Integrated in the Chromosome.染色体上同时整合了[具体内容缺失]和[具体内容缺失]的多重耐药肺炎克雷伯菌的出现与进化
Antimicrob Agents Chemother. 2017 Jun 27;61(7). doi: 10.1128/AAC.00076-17. Print 2017 Jul.
2
Chromosomal Integration of the Klebsiella pneumoniae Carbapenemase Gene, , in Klebsiella Species Is Elusive but Not Rare.肺炎克雷伯菌碳青霉烯酶基因在克雷伯菌属中的染色体整合难以捉摸但并不罕见。
Antimicrob Agents Chemother. 2017 Feb 23;61(3). doi: 10.1128/AAC.01823-16. Print 2017 Mar.
3
Detection of an Escherichia coli Sequence Type 167 Strain with Two Tandem Copies of blaNDM-1 in the Chromosome.检测到一株染色体上有两个串联 blaNDM-1 拷贝的大肠杆菌序列型 167 菌株。
J Clin Microbiol. 2016 Dec 28;55(1):199-205. doi: 10.1128/JCM.01581-16. Print 2017 Jan.
4
Comparative genomic analysis of Klebsiella pneumoniae subsp. pneumoniae KP617 and PittNDM01, NUHL24835, and ATCC BAA-2146 reveals unique evolutionary history of this strain.肺炎克雷伯菌肺炎亚种KP617与PittNDM01、NUHL24835及ATCC BAA - 2146的比较基因组分析揭示了该菌株独特的进化史。
Gut Pathog. 2016 Jul 11;8:34. doi: 10.1186/s13099-016-0117-1. eCollection 2016.
5
Global Dissemination of Carbapenemase-Producing Klebsiella pneumoniae: Epidemiology, Genetic Context, Treatment Options, and Detection Methods.产碳青霉烯酶肺炎克雷伯菌的全球传播：流行病学、基因背景、治疗选择及检测方法
Front Microbiol. 2016 Jun 13;7:895. doi: 10.3389/fmicb.2016.00895. eCollection 2016.
6
Clonal expansion of Escherichia coli ST38 carrying a chromosomally integrated OXA-48 carbapenemase gene.携带染色体整合型OXA-48碳青霉烯酶基因的大肠杆菌ST38的克隆扩增。
J Med Microbiol. 2016 Jun;65(6):538-546. doi: 10.1099/jmm.0.000248. Epub 2016 Mar 16.
7
Genomic Characteristics of NDM-Producing Enterobacteriaceae Isolates in Australia and Their blaNDM Genetic Contexts.澳大利亚产NDM的肠杆菌科分离株的基因组特征及其blaNDM基因背景
Antimicrob Agents Chemother. 2015 Oct 19;60(1):136-41. doi: 10.1128/AAC.01243-15. Print 2016 Jan.
8
Insertion Sequence IS26 Reorganizes Plasmids in Clinically Isolated Multidrug-Resistant Bacteria by Replicative Transposition.插入序列IS26通过复制性转座在临床分离的多重耐药细菌中重组质粒。
mBio. 2015 Jun 9;6(3):e00762. doi: 10.1128/mBio.00762-15.
9
Whole-genome assembly of Klebsiella pneumoniae coproducing NDM-1 and OXA-232 carbapenemases using single-molecule, real-time sequencing.使用单分子实时测序技术对同时产生NDM-1和OXA-232碳青霉烯酶的肺炎克雷伯菌进行全基因组组装。
Antimicrob Agents Chemother. 2014 Oct;58(10):5947-53. doi: 10.1128/AAC.03180-14. Epub 2014 Jul 28.
10
IS1R-mediated plasticity of IncL/M plasmids leads to the insertion of bla OXA-48 into the Escherichia coli Chromosome.IS1R介导的IncL/M质粒可塑性导致bla OXA-48插入大肠杆菌染色体。
Antimicrob Agents Chemother. 2014 Jul;58(7):3785-90. doi: 10.1128/AAC.02669-14. Epub 2014 Apr 21.

产碳青霉烯酶肺炎克雷伯菌的染色体携带. 基因的基因组特征

Genomic Characterization of Carbapenemase-Producing Klebsiella pneumoniae with Chromosomally Carried .

机构信息

Japan-Thailand Research Collaboration Center for Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.

Japan-Thailand Research Collaboration Center for Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan

出版信息

Antimicrob Agents Chemother. 2018 Nov 26;62(12). doi: 10.1128/AAC.01520-18. Print 2018 Dec.

DOI:10.1128/AAC.01520-18
PMID:30323033
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6256778/
Abstract

We report here strains carrying chromosomal in Thailand. The genomes of these two isolates include a 160-kbp insertion containing , which is almost identical to that in the IncHI1B-like plasmid. Further analysis indicated that IS-mediated intermolecular transposition and Tn transposase-mediated homologous recombination resulted in the integration of into the chromosome from an IncHI1B-like plasmid. The spread of this type of carbapenem-resistant may threaten public health and warrants further monitoring.

摘要

我们在此报告泰国携带染色体的 菌株。这两个分离株的基因组包含一个 160-kbp 的插入片段，其中包含 ，几乎与 IncHI1B 样质粒中的相同。进一步分析表明，IS 介导的分子间转位和 Tn 转座酶介导的同源重组导致 从 IncHI1B 样质粒整合到染色体中。这种碳青霉烯类耐药 的传播可能会威胁到公众健康，需要进一步监测。