Takeda K
Jpn J Physiol. 1977;27(3):379-89. doi: 10.2170/jjphysiol.27.379.
The sarcotubular system of frog sartorius muscle fibers is found to generate a prolonged depolarizing regenerative response under appropriate experimental conditions. It is shown from a point-voltage clamp analysis that the inward current component responsible for the response lasts on depolarization for hundreds of milliseconds, and reverses its sign when an equilibrium potential is exceeded. The sarcotubular response occurs in F-Ringer solution and is enhanced with EDTA. It also occurs in normal or propionate-Ringer solution containing EDTA without great change in the equilibrium potential. The response is inhibited reversibly with picrotoxin. Partial replacement of Na by K in the propionate-Ringer solution reduces the inward current component which suggests that Na may be the responsible ions.
在适当的实验条件下，发现青蛙缝匠肌纤维的肌管系统会产生一种持续时间较长的去极化再生反应。通过点电压钳分析表明，负责该反应的内向电流成分在去极化时持续数百毫秒，并且当超过平衡电位时其符号会反转。肌管反应在F - 林格溶液中出现，并在EDTA存在时增强。它也发生在含有EDTA的正常或丙酸盐 - 林格溶液中，平衡电位没有太大变化。该反应可被印防己毒素可逆性抑制。在丙酸盐 - 林格溶液中用K部分替代Na会降低内向电流成分，这表明Na可能是相关离子。
