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在一例超大剂量输血病例中机构协议和重点心脏超声检查的价值

The value of institutional protocols and focused cardiac ultrasound during a case of ultramassive transfusion.

作者信息

Tahir Janjua Muhammad Salman, Agarwal Shvetank, Castresana Manuel R

机构信息

Department of Anesthesiology and Perioperative Medicine, Medical College of Georgia at Augusta University, Augusta, GA, USA.

出版信息

Ann Card Anaesth. 2018 Oct-Dec;21(4):433-436. doi: 10.4103/aca.ACA_49_18.

DOI:10.4103/aca.ACA_49_18
PMID:30333342
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6206793/
Abstract

A 53-year-old female was admitted to the emergency department with an exsanguinating bleed from the rectum which was of unclear origin. In what could be considered an ultramassive transfusion, 60 units packed red blood cells, 23 units fresh frozen plasma, 20 units platelets, 6 units cryoprecipitate, 30 L of crystalloids, 2 L of colloids, and 4 g of tranexamic acid were transfused over the course of 7 h. An arterio-enteric fistula was diagnosed and treated by an interventional radiologist. The patient recovered rapidly thereafter without any major neurologic, pulmonary, cardiac, or hematologic complications.

摘要

一名53岁女性因不明原因的直肠大出血被送往急诊科。在堪称超大剂量输血的过程中,7小时内输注了60单位浓缩红细胞、23单位新鲜冰冻血浆、20单位血小板、6单位冷沉淀、30升晶体液、2升胶体液和4克氨甲环酸。一名介入放射科医生诊断并治疗了动脉肠瘘。此后患者迅速康复,未出现任何严重的神经、肺部、心脏或血液系统并发症。

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本文引用的文献

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Predicting and measuring fluid responsiveness with echocardiography.用超声心动图预测和测量液体反应性。
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Morbidity and mortality after massive transfusion in patients undergoing non-cardiac surgery.非心脏手术患者大量输血后的发病率和死亡率。
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Plasma transfusion for patients with severe hemorrhage: what is the evidence?血浆输注治疗严重出血患者:有何证据?
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A review on decision support for massive transfusion: understanding human factors to support the implementation of complex interventions in trauma.创伤中大量输血决策支持的综述:理解人为因素以支持复杂干预措施的实施。
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10
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2) A randomised, placebo-controlled trial.氨甲环酸对严重出血创伤患者死亡、血管闭塞事件及输血的影响(CRASH-2):一项随机、安慰剂对照试验
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