Department of Dermatology, Andrology and STDs, Mansoura University, Mansoura, Egypt.
Department of Dermatology, Andrology and STDs, Port Said University, Port Said, Egypt.
Indian J Dermatol Venereol Leprol. 2020 Mar-Apr;86(2):158-161. doi: 10.4103/ijdvl.IJDVL_540_17.
Rosai-Dorfman disease or sinus histiocytosis with massive lymphadenopathy is a benign lympho-histiocytic proliferative disorder initially described with bilateral painless lymphadenopathy (90 %), fever, leukocytosis, elevated ESR, anemia, and polyclonal hypergammaglobulinemia (90 %). Extranodal forms occur in 43% of cases, the skin being the most common site. Around 10% of patients have skin lesions and in 3%, the disease is limited exclusively to the skin. Here, we report a male patient who presented with pure cutaneous lesions which mimic eruptive xanthoma clinically. However, the diagnosis was established histo pathologically. So, high level of clinical suspension is critical to avoid missing such cases.
罗-道二氏病或伴有巨大淋巴结病的窦组织细胞增生症是一种良性淋巴组织细胞增生性疾病，最初表现为双侧无痛性淋巴结病（90%）、发热、白细胞增多、血沉升高、贫血和多克隆高丙种球蛋白血症（90%）。43%的病例发生结外形式，皮肤是最常见的部位。约 10%的患者有皮肤病变，3%的患者疾病仅限于皮肤。在这里，我们报告了一名男性患者，他表现为单纯性皮肤病变，临床上类似于发疹性黄色瘤。然而，诊断是通过组织病理学建立的。因此，高度的临床怀疑对于避免漏诊此类病例至关重要。
