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肺部脓肿分枝杆菌感染合并反应性AA型淀粉样变性:一例报告并文献简要回顾

Pulmonary Mycobacterium abscessus Infection with Reactive AA Amyloidosis: A Case Report and Brief Review of the Literature.

作者信息

Torii Ryo, Noguchi Shingo, Shimabukuro Ikuko, Inokuchi Yuri, Tabaru Akinari, Yoshii Chiharu, Yatera Kazuhiro

机构信息

Department of Respiratory Medicine, Wakamatsu Hospital of the University of Occupational and Environmental Health, Japan.

Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan.

出版信息

Intern Med. 2019 Feb 15;58(4):557-561. doi: 10.2169/internalmedicine.1263-18. Epub 2018 Oct 17.

Abstract

We herein report a case involving a 64-year-old Japanese woman with a pulmonary Mycobacterium abscessus infection complicated by reactive AA amyloidosis, which, to our knowledge, has not been reported to date. The patient underwent gastrointestinal endoscopy for diarrhea during the treatment of pulmonary M. abscessus infection and was diagnosed with AA amyloidosis according to the histopathological findings from the endoscopic specimen. She died four months later. The prognosis of AA amyloidosis associated with pulmonary M. abscessus infection may be very poor, and physicians should pay attention to this rare condition when difficult-to-treat diarrhea occurs in patients with pulmonary M. abscessus infection.

摘要

我们在此报告一例病例,患者为一名64岁的日本女性,患有肺部脓肿分枝杆菌感染,并并发反应性AA型淀粉样变性,据我们所知,迄今为止尚未有此类报告。该患者在肺部脓肿分枝杆菌感染治疗期间因腹泻接受了胃肠内镜检查,并根据内镜标本的组织病理学检查结果被诊断为AA型淀粉样变性。四个月后她去世了。与肺部脓肿分枝杆菌感染相关的AA型淀粉样变性预后可能非常差,当肺部脓肿分枝杆菌感染患者出现难以治疗的腹泻时,医生应注意这种罕见情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b3b/6421137/4ffbdc4bbd35/1349-7235-58-0557-g001.jpg

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