Emerg Infect Dis. 2018 Nov;24(11):2036-2040. doi: 10.3201/eid2411.180368.
To determine the epidemiology of Candida auris in South Africa, we reviewed data from public- and private-sector diagnostic laboratories that reported confirmed and probable cases of invasive disease and colonization for October 2012-November 2016. We defined a case as a first isolation of C. auris from any specimen from a person of any age admitted to any healthcare facility in South Africa. We defined probable cases as cases where the diagnostic laboratory had used a nonconfirmatory biochemical identification method and C. haemulonii was cultured. We analyzed 1,692 cases; 93% were from private-sector healthcare facilities, and 92% of cases from known locations were from Gauteng Province. Of cases with available data, 29% were invasive infections. The number of cases increased from 18 (October 2012-November 2013) to 861 (October 2015-November 2016). Our results show a large increase in C. auris cases during the study period, centered on private hospitals in Gauteng Province.
为了确定南非假丝酵母菌的流行病学情况，我们对 2012 年 10 月至 2016 年 11 月期间来自公共和私营部门诊断实验室报告的确诊和疑似侵袭性疾病和定植病例的数据进行了审查。我们将病例定义为从南非任何医疗机构任何年龄段的人身上的任何标本中首次分离出假丝酵母菌的情况。我们将疑似病例定义为诊断实验室使用非确认性生化鉴定方法培养出半形假丝酵母菌的病例。我们分析了 1692 例病例；93%来自私营部门的医疗机构，92%来自已知地点的病例来自豪登省。在有可用数据的病例中，29%为侵袭性感染。病例数量从 2012 年 10 月至 2013 年 11 月的 18 例增加到 2015 年 10 月至 2016 年 11 月的 861 例。我们的研究结果表明，在研究期间，以豪登省的私立医院为中心，假丝酵母菌的病例数量大幅增加。
