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前纵隔巨大原发性脂肪肉瘤:一例报告。

Giant primary liposarcoma of the anterior mediastinum: A case report.

作者信息

Yang Yu-Shang, Bai Cheng-Yun, Li Zhong-Cheng, Li Wen-Jun, Li Yong

机构信息

Department of Thoracic Surgery, West China Hospital of Sichuan University, Chengdu, Sichuan.

Department of Thoracic Surgery, Affiliated Hospital of Qinghai University, Xining, Qinghai, China.

出版信息

Medicine (Baltimore). 2018 Oct;97(42):e12873. doi: 10.1097/MD.0000000000012873.

Abstract

RATIONALE

Liposarcoma is a cancerous mesenchymal tumor and the most common soft-tissue sarcoma that starts in the adipose tissue. Liposarcoma is commonly found in lower extremities and retroperitoneum, but rarely occurs in the mediastinum.

PATIENT CONCERNS

A 63-year-old male was referred to our clinic with a 6-month history of chronic cough and dyspnea.

DIAGNOSE

Chest x-rays demonstrated a large mass occupying the left hemithorax. Contrast-enhanced computed tomography (CT) revealed a large mass in the anterior mediastinum, which caused the extrinsic compression of the main and left pulmonary artery and the right shift of mediastinum. Diagnosis of liposarcoma was confirmed by microscopic examination and immunohistochemistry analysis.

INTERVENTIONS

The patient underwent a thoracotomy for resection of the mediastinal lesion via left thoracic approach.

OUTCOMES

The patient discharged without any complications and has been continuing to follow up in clinic without any complaints.

LESSONS

The primary mediastinal liposarcoma is rare, and we recommend that the liposarcoma should be considered in the differential diagnosis of a patient presenting with a mediastinal mass.

摘要

理论依据

脂肪肉瘤是一种癌性间叶组织肿瘤,是最常见的起源于脂肪组织的软组织肉瘤。脂肪肉瘤常见于下肢和腹膜后,但很少发生于纵隔。

患者情况

一名63岁男性因慢性咳嗽和呼吸困难6个月前来我院就诊。

诊断

胸部X线片显示左半胸有一巨大肿块。增强计算机断层扫描(CT)显示前纵隔有一巨大肿块,导致主肺动脉和左肺动脉受到外部压迫,纵隔右移。通过显微镜检查和免疫组化分析确诊为脂肪肉瘤。

干预措施

患者接受了开胸手术,通过左胸入路切除纵隔病变。

结果

患者出院时无任何并发症,一直在门诊持续随访,无任何不适。

经验教训

原发性纵隔脂肪肉瘤罕见,对于出现纵隔肿块的患者,我们建议在鉴别诊断中考虑脂肪肉瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e678/6211889/27a996b4f0dd/medi-97-e12873-g001.jpg

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