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垂体切除术可防止促肾上腺皮质激素诱导的大鼠打哈欠和阴茎勃起。

Hypophysectomy prevents ACTH-induced yawning and penile erection in rats.

作者信息

Serra G, Fratta W, Collu M, Gessa G L

出版信息

Pharmacol Biochem Behav. 1987 Feb;26(2):277-9. doi: 10.1016/0091-3057(87)90118-3.

DOI:10.1016/0091-3057(87)90118-3
PMID:3033697
Abstract

The intracerebroventricular administration of ACTH1-24 (3-5 micrograms/rat) produced a behavioural syndrome characterized by recurrent episodes of penile erection and yawning in rats. Hypophysectomy prevented ACTH1-24-induced yawning and penile erection. These results suggest that pituitary has a "trophic" action not only on peripheral target organs but also on structures in brain controlling specific behavioural responses.

摘要

向大鼠脑室内注射促肾上腺皮质激素1 - 24(3 - 5微克/只大鼠)会产生一种行为综合征,其特征为大鼠反复出现阴茎勃起和打哈欠。垂体切除可阻止促肾上腺皮质激素1 - 24诱导的打哈欠和阴茎勃起。这些结果表明,垂体不仅对周围靶器官有“营养”作用,而且对控制特定行为反应的脑内结构也有“营养”作用。

相似文献

1
Hypophysectomy prevents ACTH-induced yawning and penile erection in rats.垂体切除术可防止促肾上腺皮质激素诱导的大鼠打哈欠和阴茎勃起。
Pharmacol Biochem Behav. 1987 Feb;26(2):277-9. doi: 10.1016/0091-3057(87)90118-3.
2
Monosodium glutamate does not alter ACTH- or apomorphine-induced penile erection and yawning.味精不会改变促肾上腺皮质激素或阿扑吗啡诱导的阴茎勃起和打哈欠。
Pharmacol Biochem Behav. 1987 Mar;26(3):503-7. doi: 10.1016/0091-3057(87)90156-0.
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d(CH2)5Tyr(Me)-[Orn8]vasotocin, a potent oxytocin antagonist, antagonizes penile erection and yawning induced by oxytocin and apomorphine, but not by ACTH-(1-24).d(CH2)5Tyr(Me)-[Orn8]血管紧张素,一种有效的催产素拮抗剂,可拮抗由催产素和阿扑吗啡诱导的阴茎勃起和打哈欠,但对促肾上腺皮质激素(1-24)诱导的阴茎勃起和打哈欠无拮抗作用。
Eur J Pharmacol. 1987 Feb 10;134(2):221-4. doi: 10.1016/0014-2999(87)90168-3.
4
Paraventricular nucleus lesion prevents yawning and penile erection induced by apomorphine and oxytocin but not by ACTH in rats.
Brain Res. 1987 Sep 22;421(1-2):349-52. doi: 10.1016/0006-8993(87)91305-9.
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Oxytocin-induced penile erection and yawning in male rats: effect of neonatal monosodium glutamate and hypophysectomy.催产素诱导雄性大鼠阴茎勃起和打哈欠:新生期谷氨酸钠和垂体切除术的影响
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Role of calcium in the expression of ACTH-induced stretching, yawning and penile erection.钙在促肾上腺皮质激素诱导的伸展、打哈欠和阴茎勃起表达中的作用。
Brain Res Bull. 1990 Jun;24(6):853-6. doi: 10.1016/0361-9230(90)90151-o.
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Effect of excitatory amino acid receptor antagonists on apomorphine-, oxytocin- and ACTH-induced penile erection and yawning in male rats.兴奋性氨基酸受体拮抗剂对雄性大鼠中阿扑吗啡、催产素和促肾上腺皮质激素诱导的阴茎勃起及呵欠的影响。
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Central dopamine-oxytocin-adrenocorticotropin link in the expression of yawning and penile erection.打哈欠和阴茎勃起表达中的中枢多巴胺-催产素-促肾上腺皮质激素联系
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Oxytocin: an extremely potent inducer of penile erection and yawning in male rats.
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Hypophysectomy prevents yawning and penile erection but not hypomotility induced by apomorphine.垂体切除术可防止打哈欠和阴茎勃起,但不能防止阿扑吗啡引起的运动减退。
Pharmacol Biochem Behav. 1983 Dec;19(16):917-9. doi: 10.1016/0091-3057(83)90390-8.

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Central nervous system agents in the treatment of erectile dysfunction: how do they work?
Curr Urol Rep. 2001 Dec;2(6):488-94. doi: 10.1007/s11934-001-0044-6.
2
Oxytocin-induced penile erection and yawning in male rats: effect of neonatal monosodium glutamate and hypophysectomy.催产素诱导雄性大鼠阴茎勃起和打哈欠:新生期谷氨酸钠和垂体切除术的影响
Psychopharmacology (Berl). 1989;97(3):383-7. doi: 10.1007/BF00439455.
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The effects of dihydropyridine compounds in behavioural tests of dopaminergic activity.二氢吡啶类化合物在多巴胺能活性行为测试中的作用。
Br J Pharmacol. 1989 Dec;98(4):1312-8. doi: 10.1111/j.1476-5381.1989.tb12679.x.
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Yawning induced by apomorphine, physostigmine or pilocarpine is potentiated by dihydropyridine calcium channel blockers.
Psychopharmacology (Berl). 1990;100(2):168-72. doi: 10.1007/BF02244401.