Jambo Abera, Mengistu Getnet, Sisay Mekonnen, Amare Firehiwot, Edessa Dumessa
Department of Clinical Pharmacy, School of Pharmacy, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.
Department of Pharmacy, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Front Pharmacol. 2018 Sep 25;9:1063. doi: 10.3389/fphar.2018.01063. eCollection 2018.
Self-medication has been increasing in many developing and developed countries. Its use during pregnancy presents a major challenge due to potential undesirable effects on mother and the fetus. So the aim of this study was to assess the prevalence of self-medication and contributing factors, among pregnant women. Institution based cross sectional study was conducted among 244 pregnant women attending antenatal care at Hiwot Fana Specialized University Hospital and Jugal Hospital from February to March, 2017. A structured questionnaire based interview was used to collect data from each study subject. Then, data were categorized and analyzed using SPSS version 20 software. Logistic regression analysis was used to determine the significance of the association between the outcome and independent variables. -value <0.05 was considered as a statistically significant in multivariate analysis. The prevalence of self-medication during current pregnancy was 69.4%; out of which, 40.6% uses only herbal medicines to self-medicate. Time saving (50.7%) and prior experience of the drug (25.35%) were the main reasons for self-medication using conventional medicines while fewer side effects (59.86%) and effectiveness (35.92%) were the common reasons for self-medication using herbal medicines. Common cold and headache were among the common indications for self-medication. Friends (28.17%) and the pharmacist/druggist (23.94%) were the commonest source of information for conventional medicines while family/friends (69.72%) and neighbors (26.76%) were the common source of information for herbal medicines. Community drug retail outlets and neighbors were the commonly used sources of conventional medicines; while market place and self-preparation were the common sources of herbal medicines. Previous history of self-medication was significantly associated ( < 0.05) with current self-medication with conventional drugs and being a farmer by occupation and poor monthly income were significantly associated with herbal medicine use during pregnancy ( < 0.05). The prevalence of self-medication during pregnancy was very high in this study which showed a need for public trainings for all women of reproductive age about the risks of inappropriate self-medication.
自我药疗在许多发展中国家和发达国家都呈上升趋势。孕期使用自我药疗对母亲和胎儿存在潜在不良影响,是一项重大挑战。因此,本研究旨在评估孕妇中自我药疗的患病率及相关影响因素。2017年2月至3月,在Hiwot Fana专科医院和Jugal医院对244名接受产前检查的孕妇进行了基于机构的横断面研究。采用结构化问卷调查对每个研究对象收集数据。然后,使用SPSS 20版软件对数据进行分类和分析。采用逻辑回归分析确定结果与自变量之间关联的显著性。多因素分析中,P值<0.05被认为具有统计学意义。本次孕期自我药疗的患病率为69.4%;其中,40.6%仅使用草药进行自我药疗。节省时间(50.7%)和药物的既往使用经验(25.35%)是使用传统药物进行自我药疗的主要原因,而副作用较少(59.86%)和疗效(35.92%)是使用草药进行自我药疗的常见原因。普通感冒和头痛是自我药疗的常见适应症。朋友(28.17%)和药剂师/药商(23.94%)是传统药物最常见的信息来源,而家人/朋友(69.72%)和邻居(26.76%)是草药的常见信息来源。社区药店和邻居是传统药物常用的获取渠道;而市场和自行配制是草药的常见来源。既往自我药疗史与当前使用传统药物进行自我药疗显著相关(P<0.05),职业为农民且月收入低与孕期使用草药显著相关(P<0.05)。本研究中孕期自我药疗的患病率非常高,这表明需要对所有育龄妇女进行关于不当自我药疗风险的公共培训。