Bao Zhijun, Zhang Kui, Jian Jingyi, Hu Ziwei, Yuan Kaisong, Shao Huikai, Peng Kun, Jiang Zhengjin, Zapien Juan Antonio, Yan Yehan, Zhang Cheng, Zhou Haibo
Institute of Pharmaceutical Analysis, College of Pharmacy, Jinan University, Guangzhou, 510632, Guangdong, China.
School of Chemistry and Chemical Engineering, Anhui University of Technology, Ma'anshan, 243032, Anhui, China.
Mikrochim Acta. 2018 Oct 18;185(11):507. doi: 10.1007/s00604-018-3049-2.
This paper describes the synthesis of fluorescent copper nanoclusters (CuNC) with a fluorescence quantum yield as high as 2.3% after modification with cysteamine. The modified CuNC are shown to be viable probes for the determination of picric acid (PA). Fluorescence drops with increasing concentration of PA which can be detected fluorometrically with a 0.14 μM limit of detection. This is much lower than required by the People's Republic of China Surface Water Environmental Quality Standard (2.2 μM). The probe was successfully applied to the determination of PA in spiked tap water, lake water and river water. Graphical abstract Copper nanoclusters (CuNC) have weak fluorescence but after the modification with cysteamine, the fluorescence of CuNC is strongly enhanced. The fluorescence of such cysteamine-coated copper nanoclusters (CuNC-CA) is reduced upon the addition of picric acid (PA) through an inner filter effect (IFE).
本文描述了用半胱胺修饰后荧光量子产率高达2.3%的荧光铜纳米簇（CuNC）的合成。结果表明，修饰后的CuNC是测定苦味酸（PA）的可行探针。随着PA浓度的增加荧光强度下降，其荧光检测限为0.14 μM。这远低于中华人民共和国地表水环境质量标准要求的2.2 μM。该探针已成功应用于加标自来水、湖水和河水中PA的测定。图形摘要铜纳米簇（CuNC）荧光较弱，但经半胱胺修饰后，CuNC的荧光得到显著增强。通过内滤效应（IFE），加入苦味酸（PA）后，这种半胱胺包覆的铜纳米簇（CuNC-CA）的荧光会减弱。
