[Surface analysis of Bio-Sinter ceramic specimens using Rutherford backscattering spectrometry following subcutaneous implantation].

The formation of a calcium and phosphorous containing surface-layer is one of the essential suppositions of bioactive materials for the replace of bone. In the submitted study on sintered Bio-Vitro-ceramic specimens, which where explanted from the subcutaneous tissues of rats after 20, 40, 90 and 180 days, a relative increase of calcium content, and an absolute increase of phosphorous content of the direct surface of the specimens (approximately 0.01 micron) could be demonstrated. In contrast to not implanted specimens the values of silicat were 90% lower. After 180 days of implantation the distribution of elements at the surface of all types of sintered specimens had been stabilized 1.6 (Ap40KS15), 7.1 (Ap40KS30), 2.3 (Ap40SV).