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两种新型温和噬菌体感染酿脓链球菌：它们的基因组、形态和稳定性。

Two novel temperate bacteriophages infecting Streptococcus pyogenes: Their genomes, morphology and stability.

机构信息

Bacteriophage Laboratory, Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Weigla 12, Wrocław, Poland.

Department of Molecular Virology, Faculty of Biology, Adam Mickiewicz University, Collegium Biologicum-Umultowska 89, Poznan, Poland.

出版信息

PLoS One. 2018 Oct 19;13(10):e0205995. doi: 10.1371/journal.pone.0205995. eCollection 2018.

DOI:10.1371/journal.pone.0205995
PMID:30339682
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6195288/
Abstract

Only 3% of phage genomes in NCBI nucleotide database represent phages that are active against Streptococcus sp. With the aim to increase general awareness of phage diversity, we isolated two bacteriophages, Str01 and Str03, active against health-threatening Group A Streptococcus (GAS). Both phages are members of the Siphoviridae, but their analysis revealed that Str01 and Str03 do not belong to any known genus. We identified their structural proteins based on LC-ESI29 MS/MS and list their basic thermal stability and physico-chemical features including optimum pH. Annotated genomic sequences of the phages are deposited in GenBank (NCBI accession numbers KY349816 and KY363359, respectively).

摘要

在 NCBI 核苷酸数据库中，仅有 3%的噬菌体基因组代表了对链球菌属具有活性的噬菌体。为了提高人们对噬菌体多样性的普遍认识，我们分离到了两种针对健康威胁性 A 组链球菌（GAS）的噬菌体，Str01 和 Str03。这两种噬菌体均属于长尾噬菌体科，但分析表明 Str01 和 Str03 不属于任何已知属。我们根据 LC-ESI29 MS/MS 鉴定了它们的结构蛋白，并列出了它们的基本热稳定性和理化特性，包括最适 pH 值。噬菌体的注释基因组序列已分别存入 GenBank（NCBI 登录号为 KY349816 和 KY363359）。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72c1/6195288/b76ba5786295/pone.0205995.g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72c1/6195288/4edc13681e57/pone.0205995.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72c1/6195288/5263720e6b23/pone.0205995.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72c1/6195288/d498824acb3d/pone.0205995.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72c1/6195288/729f76abad66/pone.0205995.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72c1/6195288/65515375ced7/pone.0205995.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72c1/6195288/b76ba5786295/pone.0205995.g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72c1/6195288/4edc13681e57/pone.0205995.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72c1/6195288/5263720e6b23/pone.0205995.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72c1/6195288/d498824acb3d/pone.0205995.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72c1/6195288/729f76abad66/pone.0205995.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72c1/6195288/65515375ced7/pone.0205995.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72c1/6195288/b76ba5786295/pone.0205995.g006.jpg

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1
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Arch Virol. 2018 Apr;163(4):1125-1129. doi: 10.1007/s00705-018-3723-z. Epub 2018 Jan 22.
2
Database resources of the National Center for Biotechnology Information.国家生物技术信息中心数据库资源。
Nucleic Acids Res. 2018 Jan 4;46(D1):D8-D13. doi: 10.1093/nar/gkx1095.
3
Taxonomy of prokaryotic viruses: 2016 update from the ICTV bacterial and archaeal viruses subcommittee.
Beni Suef Univ J Basic Appl Sci. 2021;10(1):49. doi: 10.1186/s43088-021-00141-8. Epub 2021 Aug 28.
4
Survival Strategies of in Response to Phage Infection.在噬菌体感染下的生存策略。
Viruses. 2021 Apr 2;13(4):612. doi: 10.3390/v13040612.
5
Characterization of the First Virulent Phage Infecting , the Queen of the Cellars.首个感染酒窖女王（某种微生物）的烈性噬菌体的特性分析
Front Microbiol. 2021 Jan 13;11:596541. doi: 10.3389/fmicb.2020.596541. eCollection 2020.
6
Long-read metagenomics using PromethION uncovers oral bacteriophages and their interaction with host bacteria.基于 PromethION 的长读宏基因组学揭示了口腔噬菌体及其与宿主细菌的相互作用。
Nat Commun. 2021 Jan 4;12(1):27. doi: 10.1038/s41467-020-20199-9.
7
Characterization of Clinical and Carrier and Prophage Contribution to the Strain Variability.临床和携带者特征以及噬菌体对菌株变异性的贡献。
Viruses. 2020 Nov 18;12(11):1323. doi: 10.3390/v12111323.
8
Characterization of Bacteriophage Peptides of Pathogenic by LC-ESI-MS/MS: Bacteriophage Phylogenomics and Their Relationship to Their Host.通过液相色谱-电喷雾串联质谱法对致病性噬菌体肽进行表征：噬菌体系统发育基因组学及其与宿主的关系
Front Microbiol. 2020 Jun 9;11:1241. doi: 10.3389/fmicb.2020.01241. eCollection 2020.
9
Characterization of a Highly Virulent Strain Isolated From Greek Aquaculture, and a Spontaneously Induced Prophage Therein.从希腊水产养殖中分离出的高毒力菌株及其自发诱导的原噬菌体的特性分析。
Front Microbiol. 2019 Feb 6;10:141. doi: 10.3389/fmicb.2019.00141. eCollection 2019.
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5
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7
Horizontal DNA Transfer Mechanisms of Bacteria as Weapons of Intragenomic Conflict.细菌的水平DNA转移机制作为基因组内冲突的武器
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10
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Front Microbiol. 2014 Jan 24;5:7. doi: 10.3389/fmicb.2014.00007. eCollection 2014.