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mA-mediated translation regulation.mA介导的翻译调控。
Biochim Biophys Acta Gene Regul Mech. 2019 Mar;1862(3):301-309. doi: 10.1016/j.bbagrm.2018.10.006. Epub 2018 Oct 17.
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Internal 6-methyladenine residues increase the in vitro translation efficiency of dihydrofolate reductase messenger RNA.内部6-甲基腺嘌呤残基提高了二氢叶酸还原酶信使核糖核酸的体外翻译效率。
Int J Biochem Cell Biol. 1996 Jul;28(7):823-9. doi: 10.1016/1357-2725(96)00014-3.
3
Acetylation Enhances mRNA Stability and Translation.乙酰化增强mRNA稳定性和翻译。
Biochemistry. 2019 Mar 26;58(12):1553-1554. doi: 10.1021/acs.biochem.9b00061. Epub 2019 Mar 15.
4
Readers of the mA epitranscriptomic code.mA 表转录组学密码的读者。
Biochim Biophys Acta Gene Regul Mech. 2019 Mar;1862(3):329-342. doi: 10.1016/j.bbagrm.2018.12.008. Epub 2019 Jan 17.
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Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element.丝裂原活化蛋白激酶激活的蛋白激酶2主要通过改变锌指蛋白16 mRNA的表达、稳定性以及与富含腺嘌呤/尿嘧啶元件的结合来调节肿瘤坏死因子mRNA的稳定性和翻译。
Mol Cell Biol. 2006 Mar;26(6):2399-407. doi: 10.1128/MCB.26.6.2399-2407.2006.
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A profusion of controls.大量的控制措施。
J Cell Biol. 1988 Jul;107(1):1-7. doi: 10.1083/jcb.107.1.1.
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MicroRNA-mediated mRNA deadenylation and repression of protein synthesis in a mammalian cell-free system.微小RNA介导的mRNA去腺苷酸化及在哺乳动物无细胞系统中对蛋白质合成的抑制
Prog Mol Subcell Biol. 2010;50:85-97. doi: 10.1007/978-3-642-03103-8_6.
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Metabolic influences on RNA biology and translation.代谢对RNA生物学及翻译的影响。
Crit Rev Biochem Mol Biol. 2017 Apr;52(2):176-184. doi: 10.1080/10409238.2017.1283294. Epub 2017 Feb 2.
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mA mRNA modification regulates mammalian spermatogenesis.mA 信使 RNA 修饰调控哺乳动物精子发生。
Biochim Biophys Acta Gene Regul Mech. 2019 Mar;1862(3):403-411. doi: 10.1016/j.bbagrm.2018.10.016. Epub 2018 Nov 2.
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RNA regulation: a new genetics?RNA调控：一种新的遗传学？
Nat Rev Genet. 2004 Apr;5(4):316-23. doi: 10.1038/nrg1321.
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Differential control of RNA demethylase activity and selectivity by cofactor ascorbate.辅因子抗坏血酸对RNA去甲基化酶活性和选择性的差异调控
bioRxiv. 2025 May 8:2025.05.06.652568. doi: 10.1101/2025.05.06.652568.
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The RNA mA landscape during human oocyte-to-embryo transition.人类卵母细胞向胚胎转变过程中的RNA mA图谱。
EMBO J. 2025 Jun 4. doi: 10.1038/s44318-025-00474-5.
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Coupling mechanisms coordinating mRNA translation with stages of the mRNA lifecycle.将mRNA翻译与mRNA生命周期各阶段相协调的偶联机制。
RNA Biol. 2025 Dec;22(1):1-12. doi: 10.1080/15476286.2025.2483001. Epub 2025 Mar 24.
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The Role of MA Modification in Autoimmunity: Emerging Mechanisms and Therapeutic Implications.甲基化修饰在自身免疫中的作用：新出现的机制及治疗意义
Clin Rev Allergy Immunol. 2025 Mar 14;68(1):29. doi: 10.1007/s12016-025-09041-6.
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Structural Features of 5' Untranslated Region in Translational Control of Eukaryotes.真核生物翻译控制中5'非翻译区的结构特征
Int J Mol Sci. 2025 Feb 25;26(5):1979. doi: 10.3390/ijms26051979.
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Nucleotide-resolution Mapping of RNA N6-Methyladenosine (m6A) modifications and comprehensive analysis of global polyadenylation events in mRNA 3' end processing in malaria pathogen .疟原虫中RNA N6-甲基腺苷（m6A）修饰的核苷酸分辨率图谱绘制及mRNA 3'端加工过程中全局多聚腺苷酸化事件的综合分析
bioRxiv. 2025 Jan 8:2025.01.07.631827. doi: 10.1101/2025.01.07.631827.
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POU4F1 enhances lung cancer gemcitabine resistance by regulating METTL3-dependent TWF1 mRNA N6 adenosine methylation.POU4F1通过调节METTL3依赖的TWF1 mRNA N6腺苷甲基化增强肺癌吉西他滨耐药性。
3 Biotech. 2025 Jan;15(1):7. doi: 10.1007/s13205-024-04161-w. Epub 2024 Dec 12.
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N-Methyladenosine Modification on the Function of Female Reproductive Development and Related Diseases.N-甲基腺苷修饰对雌性生殖发育及相关疾病功能的影响
Immun Inflamm Dis. 2024 Dec;12(12):e70089. doi: 10.1002/iid3.70089.
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Long-read RNA sequencing reveals allele-specific -methyladenosine modifications.长读长RNA测序揭示了等位基因特异性N6-甲基腺苷修饰。
Genome Res. 2025 Apr 14;35(4):999-1011. doi: 10.1101/gr.279270.124.
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Long-read RNA sequencing reveals allele-specific N-methyladenosine modifications.长读长RNA测序揭示了等位基因特异性N-甲基腺苷修饰。
bioRxiv. 2024 Sep 5:2024.07.08.602538. doi: 10.1101/2024.07.08.602538.
本文引用的文献
1
mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis.METTL3-eIF3h 通过 mRNA 环化增强翻译并促进致癌作用。
Nature. 2018 Sep;561(7724):556-560. doi: 10.1038/s41586-018-0538-8. Epub 2018 Sep 19.
2
Differential mA, mA, and mA Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm.FTO 在细胞核和细胞质中介导的差异 mA、mA 和 mA 去甲基化。
Mol Cell. 2018 Sep 20;71(6):973-985.e5. doi: 10.1016/j.molcel.2018.08.011. Epub 2018 Sep 6.
3
Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development.核 m6A 阅读器 YTHDC1 调节小鼠卵母细胞发育过程中的可变多聚腺苷酸化和剪接。
PLoS Genet. 2018 May 25;14(5):e1007412. doi: 10.1371/journal.pgen.1007412. eCollection 2018 May.
4
Recognition of RNA N-methyladenosine by IGF2BP proteins enhances mRNA stability and translation.IGF2BP 蛋白对 RNA N6-甲基腺苷的识别增强了 mRNA 的稳定性和翻译。
Nat Cell Biol. 2018 Mar;20(3):285-295. doi: 10.1038/s41556-018-0045-z. Epub 2018 Feb 23.
5
Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication.SV40 晚期 mRNA 上 m6A 的添加增强了病毒结构基因的表达和复制。
PLoS Pathog. 2018 Feb 15;14(2):e1006919. doi: 10.1371/journal.ppat.1006919. eCollection 2018 Feb.
6
N-Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response.N6-甲基腺苷指导整合应激反应中的 mRNA 选择性翻译。
Mol Cell. 2018 Feb 15;69(4):636-647.e7. doi: 10.1016/j.molcel.2018.01.019. Epub 2018 Feb 8.
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High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies.高密度接近映射揭示了 mRNA 相关颗粒和体的亚细胞组织。
Mol Cell. 2018 Feb 1;69(3):517-532.e11. doi: 10.1016/j.molcel.2017.12.020. Epub 2018 Jan 25.
8
Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules.应激颗粒内蛋白相互作用的上下文相关和疾病特异性多样性。
Cell. 2018 Jan 25;172(3):590-604.e13. doi: 10.1016/j.cell.2017.12.032.
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Epitranscriptomic mA Regulation of Axon Regeneration in the Adult Mammalian Nervous System.转录后 mA 调控成年哺乳动物神经系统中的轴突再生。
Neuron. 2018 Jan 17;97(2):313-325.e6. doi: 10.1016/j.neuron.2017.12.036.
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Dynamic m6A modification regulates local translation of mRNA in axons.动态 m6A 修饰调节 mRNA 在轴突中的局部翻译。
Nucleic Acids Res. 2018 Feb 16;46(3):1412-1423. doi: 10.1093/nar/gkx1182.
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