Chehab Omar, Qannus Abdul Salam, Eldirani Mahmoud, Hassan Hussein, Tamim Hani, Dakik Habib A
Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Drs Omar Chehab and Abdul Salam Qannus had equal contribution to this study.
Cardiol Res. 2018 Oct;9(5):293-299. doi: 10.14740/cr772w. Epub 2018 Oct 7.
Limited data are available on the predictors of mortality in patients hospitalized with acute myocardial infarction (AMI) in developing countries. In this study, we analyze the predictors for in--hospital mortality in patients hospitalized with AMI (ST segment elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI)) in a large tertiary referral university hospital in Lebanon.
This was a retrospective study of 503 patients admitted to the American University of Beirut Medical Center with AMI (228 with STEMI and 275 with NSTEMI).
The in-hospital mortality rate was 7.8%. The multivariate predictors of mortality in the overall population were similar to what has been reported in large registries in the USA and Europe. They included older age (> 65 years) (OR = 2.99, 95% CI = 1.22 - 7.36, P = 0.02), systolic blood pressure < 100 mm Hg (OR = 2.75, 95% CI = 1.12 - 6.76, P = 0.03), history of stroke (OR = 4.28, 95% CI = 1.29 - 14.17, P = 0.02), history of coronary artery bypass graft (CABG) (OR = 2.68, 95% CI = 1.15 - 6.23, P = 0.02), heart failure (OR = 3.92, CI = 1.62 - 9.49, P = 0.002) and ejection fraction (EF) < 35% (OR = 2.32, 95% CI = 1.05 - 5.14, P = 0.04). In a separate analysis of STEMI and NSTEMI patients, age, heart failure and a low EF continued to be multivariate predictors of mortality in both subgroups. In addition, prior stroke was an added predictor in STEMI patients, and prior CABG was an added predictor in NSTEMI.
Predictors of in-hospital mortality in patients hospitalized with AMI in a tertiary referral university hospital in the Middle East are similar to what has been reported in large registries in the USA and Europe.
在发展中国家，关于急性心肌梗死（AMI）住院患者死亡率预测因素的数据有限。在本研究中，我们分析了黎巴嫩一家大型三级转诊大学医院中 AMI（ST 段抬高型心肌梗死（STEMI）和非 ST 段抬高型心肌梗死（NSTEMI））住院患者的院内死亡预测因素。
这是一项对 503 例入住贝鲁特美国大学医疗中心的 AMI 患者的回顾性研究（228 例 STEMI 患者和 275 例 NSTEMI 患者）。
院内死亡率为 7.8%。总体人群中死亡率的多因素预测因素与美国和欧洲大型登记研究报告的相似。包括年龄较大（>65 岁）（OR = 2.99，95%CI = 1.22 - 7.36，P = 0.02）、收缩压<100 mmHg（OR = 2.75，95%CI = 1.12 - 6.76，P = 0.03）、中风史（OR = 4.28，95%CI = 1.29 - 14.17，P = 0.02）、冠状动脉旁路移植术（CABG）史（OR = 2.68，95%CI = 1.15 - 6.23，P = 0.
