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海洛因注射后由[具体病原体，原文未给出]引起的创伤性肉毒中毒。

Wound botulism caused by after a heroin injection.

作者信息

Cook Paris A, Mishler Aimee, Quan Dan, Parrish-Garcia Ashley

机构信息

Department of Pharmacy.

Department of Emergency Medicine, Maricopa Integrated Health System, University of Arizona, Phoenix, AZ, USA.

出版信息

Infect Dis Rep. 2018 Sep 5;10(2):7654. doi: 10.4081/idr.2018.7654.

DOI:10.4081/idr.2018.7654
PMID:30344967
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6176474/
Abstract

Botulism is caused by toxin production from many species of , most commonly as well as and . Development of wound botulism is associated with injection drug users but has also been described in traumatic injuries with exposure to soil. A patient presented to the emergency department with a complaint of descending, progressive weakness. He recently reported skin popping with heroin injections. Heptavalent botulinum antitoxin was obtained from the [Center for Disease Control and Prevention (CDC)]. On hospital day seven, the anaerobic wound cultures resulted with growth of .

摘要

肉毒中毒是由多种梭菌产生的毒素引起的，最常见的是肉毒杆菌，以及产气荚膜梭菌和艰难梭菌。创伤性肉毒中毒的发生与注射吸毒者有关，但也有在接触土壤的创伤性损伤中出现的报道。一名患者因进行性下行性肌无力到急诊科就诊。他最近报告有海洛因注射皮肤穿刺史。从[疾病控制和预防中心（CDC）]获得了七价肉毒抗毒素。在住院第7天，厌氧伤口培养物培养出了[具体细菌名称未给出]。

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Clin Infect Dis. 2017 Dec 27;66(suppl_1):S57-S64. doi: 10.1093/cid/cix816.
2
Clostridium subterminale septicemia in an immunocompetent patient.免疫功能正常患者的亚端孢梭菌败血症
IDCases. 2016 Jun 30;5:43-5. doi: 10.1016/j.idcr.2016.06.005. eCollection 2016.
3
Clostridium subterminale septicemia in a patient with esophageal cancer.一名食管癌患者发生亚端梭菌败血症。
IDCases. 2014 Jun 30;1(3):47-9. doi: 10.1016/j.idcr.2014.06.003. eCollection 2014.
4
Post-traumatic bone and/or joint limb infections due to Clostridium spp.创伤后梭菌属引起的骨和/或关节肢体感染
Orthop Traumatol Surg Res. 2012 Oct;98(6):696-705. doi: 10.1016/j.otsr.2012.03.019. Epub 2012 Aug 27.
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Clostridium subterminale sepsis in adult acute lymphoblastic leukemia.成人急性淋巴细胞白血病中的亚端梭菌败血症
Leuk Lymphoma. 2011 Jun;52(6):1137-8. doi: 10.3109/10428194.2011.555895.
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Recurrent wound botulism among injection drug users in California.加利福尼亚州注射吸毒者中反复发作的创伤性肉毒中毒。
Clin Infect Dis. 2011 Apr 1;52(7):862-6. doi: 10.1093/cid/cir005. Epub 2011 Feb 11.
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Wound botulism in injection drug users: time to antitoxin correlates with intensive care unit length of stay.注射吸毒者的创伤性肉毒中毒：使用抗毒素的时间与重症监护病房住院时间相关。
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