Berendsen H H, de Ley L, Poppema S, Postmus P E, Sluiter H J, The T H
Eur J Respir Dis Suppl. 1987;149:19-27.
A panel of monoclonal antibodies, detecting different intermediate sized filament proteins, was prospectively applied on all specimens derived from S.C.L.C. patients attending our clinic in 1985. Reactivity with the antibodies was subsequently correlated to clinical data. The results indicate a heterogeneous pattern of reactivity of the assessed antibodies. However this heterogeneity is not a straightforward extension of the intermediate sized filament expression in SCLC cell lines.
一组检测不同中间丝蛋白的单克隆抗体被前瞻性地应用于1985年在我们诊所就诊的小细胞肺癌（S.C.L.C.）患者的所有标本上。随后将与这些抗体的反应性与临床数据相关联。结果表明所评估抗体的反应性模式具有异质性。然而，这种异质性并非小细胞肺癌细胞系中中间丝表达的直接延伸。
