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亚临床甲状腺功能减退或中枢性甲状腺功能减退——甲状腺功能误判的风险

Subclinical hypothyroidism or central hypothyroidism-The danger of thyroid function misinterpretation.

作者信息

Anyiam Oluwaseun, Cheung Billy, Al-Sabbagh Samer

机构信息

East and North Hertfordshire NHS Trust Stevenage Hertfordshire UK.

Present address: Homerton University Hospital London UK.

出版信息

Clin Case Rep. 2018 Aug 21;6(10):1953-1957. doi: 10.1002/ccr3.1694. eCollection 2018 Oct.

DOI:10.1002/ccr3.1694
PMID:30349705
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6186879/
Abstract

Correct interpretation of thyroid function tests is critical to providing appropriate care to patients with suspected thyroid disease. It is particularly important to distinguish central hypothyroidism from other types due to the potential of concurrent secondary adrenal insufficiency and thus the need for immediate steroid replacement prior to commencing thyroxine.

摘要

正确解读甲状腺功能测试对于为疑似甲状腺疾病患者提供恰当治疗至关重要。区分中枢性甲状腺功能减退与其他类型尤为重要，因为可能并发继发性肾上腺功能不全，因此在开始使用甲状腺素之前需要立即进行类固醇替代治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a990/6186879/ffe50d99e9a2/CCR3-6-1953-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a990/6186879/c2cd4c0d0eb8/CCR3-6-1953-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a990/6186879/ffe50d99e9a2/CCR3-6-1953-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a990/6186879/c2cd4c0d0eb8/CCR3-6-1953-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a990/6186879/ffe50d99e9a2/CCR3-6-1953-g002.jpg

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本文引用的文献

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Endocrinol Diabetes Metab Case Rep. 2017 Dec 2;2017. doi: 10.1530/EDM-17-0112. eCollection 2017.
2
DIAGNOSIS OF ENDOCRINE DISEASE: Primary empty sella: a comprehensive review.内分泌疾病的诊断：原发性空蝶鞍的全面综述。
Eur J Endocrinol. 2017 Dec;177(6):R275-R285. doi: 10.1530/EJE-17-0505. Epub 2017 Aug 5.
3
The multiple genetic causes of central hypothyroidism.中枢性甲状腺功能减退症的多种遗传病因。
中枢性甲状腺功能减退症或亚临床甲状腺功能亢进症：它们会相互混淆吗？
Endocrinol Diabetes Metab Case Rep. 2020 Jul 5;2020. doi: 10.1530/EDM-20-0059.
Best Pract Res Clin Endocrinol Metab. 2017 Mar;31(2):255-263. doi: 10.1016/j.beem.2017.04.003. Epub 2017 Apr 17.
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Hypothyroidism.甲状腺功能减退症。
Lancet. 2017 Sep 23;390(10101):1550-1562. doi: 10.1016/S0140-6736(17)30703-1. Epub 2017 Mar 20.
5
ACTH Stimulation Tests for the Diagnosis of Adrenal Insufficiency: Systematic Review and Meta-Analysis.用于诊断肾上腺皮质功能不全的促肾上腺皮质激素刺激试验：系统评价与荟萃分析
J Clin Endocrinol Metab. 2016 Feb;101(2):427-34. doi: 10.1210/jc.2015-1700. Epub 2015 Dec 9.
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High incidence of adrenal crisis in educated patients with chronic adrenal insufficiency: a prospective study.慢性肾上腺皮质功能减退症患者中肾上腺危象的高发病率：一项前瞻性研究。
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