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病例报告：胸段神经鞘瘤在F-胆碱PET/CT和F-FDG PET/CT检查中均为诊断陷阱。

Case report: Thoracic schwannoma as a diagnostic pitfall in both F-Choline PET/CT and F-FDG PET/CT.

作者信息

Amrane Karim, Le Meur Coline, Alemany Pierre, Niel Clémence, Renault David, Peillon Inès, Tissot Valentin, Abgral Ronan

机构信息

Department of Oncology, Regional Hospital of Morlaix, Morlaix, France.

Inserm, UMR1227, Lymphocytes B et Autoimmunité, Univ Brest, Inserm, LabEx IGO, Brest, France.

出版信息

Front Oncol. 2024 Oct 8;14:1467344. doi: 10.3389/fonc.2024.1467344. eCollection 2024.

DOI:10.3389/fonc.2024.1467344
PMID:39439948
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11493534/
Abstract

We report increased F-FDG uptake in the right posterior mediastinal region in a 70-year-old woman following the discovery of a mass in the aftermath of a bronchitis episode. We also report increased F-Choline uptake in the right posterior mediastinal region in a 66-year-old man with newly discovered prostate cancer, which may indicate the presence of mediastinal metastases. Both patients had a thoracic MRI showing an intense gadolinium enhancement in the same region, consistent with thoracic schwannomas, which were subsequently proven histologically. This case highlights that schwannoma is a diagnostic pitfall in both F-FDG and F-Choline PET/CT.

摘要

我们报告了一名70岁女性在支气管炎发作后发现肿块，其右后纵隔区域的F-FDG摄取增加。我们还报告了一名66岁新诊断为前列腺癌的男性，其右后纵隔区域的F-胆碱摄取增加，这可能提示纵隔转移的存在。两名患者的胸部MRI均显示同一区域有强烈的钆增强，符合胸段神经鞘瘤，随后经组织学证实。该病例强调神经鞘瘤在F-FDG和F-胆碱PET/CT检查中均为诊断陷阱。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4171/11493534/3391195c81a3/fonc-14-1467344-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4171/11493534/2125ea68de4c/fonc-14-1467344-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4171/11493534/3391195c81a3/fonc-14-1467344-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4171/11493534/2125ea68de4c/fonc-14-1467344-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4171/11493534/3391195c81a3/fonc-14-1467344-g002.jpg

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本文引用的文献

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Glucose Transporters as a Target for Anticancer Therapy.葡萄糖转运蛋白作为抗癌治疗的靶点
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PET/CT and contrast-enhanced CT imaging findings in benign solitary schwannomas.良性单发施万细胞瘤的 PET/CT 和增强 CT 影像学表现。
Eur J Radiol. 2021 Aug;141:109820. doi: 10.1016/j.ejrad.2021.109820. Epub 2021 Jun 9.
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Front Med (Lausanne). 2018 Oct 8;5:275. doi: 10.3389/fmed.2018.00275. eCollection 2018.
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Clinical, Morphologic, and Pathologic Features Associated With Increased FDG Uptake in Schwannoma.与神经鞘瘤中氟代脱氧葡萄糖摄取增加相关的临床、形态学和病理学特征
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