University of Oxford, Department of Experimental Psychology, Oxford OX1 3SR, UK.
Institute of Neuroscience, Newcastle University Medical School, Newcastle upon Tyne NE2 4HH, UK.
Curr Biol. 2018 Oct 22;28(20):R1186-R1187. doi: 10.1016/j.cub.2018.09.029.
Neuroscience research in non-human primates (NHPs) has delivered fundamental knowledge about human brain function as well as some valuable therapies that have improved the lives of human patients with a variety of brain disorders. Research using NHPs, although it is facing serious challenges, continues to complement studies in human volunteers and patients, and will continue to be needed as the burdens of mental health problems and neurodegenerative diseases increase. At the same time, research into the 3Rs is helping to ameliorate the harms experienced by NHPs in experimental procedures, allowing the effective combination of optimal welfare conditions for the NHPs and high quality research.
非人类灵长类动物（NHPs）的神经科学研究为人类大脑功能提供了基础性知识，也带来了一些有价值的疗法，改善了各种脑疾病患者的生活。尽管面临严峻挑战，利用 NHPs 的研究仍在继续补充人类志愿者和患者的研究，并且随着精神健康问题和神经退行性疾病负担的增加，这种研究将继续是必要的。与此同时，对 3R 的研究有助于减轻 NHPs 在实验过程中所经历的伤害，使 NHPs 的最佳福利条件与高质量研究能够有效结合。
