前列腺癌中的单克隆丙种球蛋白病：一例报告及文献复习
Monoclonal gammopathy in prostate carcinoma: a case report and review of literature.
作者信息
Pramanik Samik, Gazi Md Jahangir, Das Anjan Kumar, Debnath Nirod Baran, Pal Salil K
机构信息
Department of General Medicine, Calcutta National Medical College, Kolkata, India.
, Flat no-1A, 876 Tagore Park, Block-C, Naskarhat, Kolkata, 700039, India.
出版信息
J Med Case Rep. 2018 Oct 25;12(1):325. doi: 10.1186/s13256-018-1811-z.
BACKGROUND
Monoclonal gammopathy is commonly associated with plasma cell dyscrasia. However, monoclonal gammopathy without bone marrow plasmacytosis in prostate carcinoma has rarely been reported. The association between the two conditions is not clearly established.
CASE PRESENTATION
We report a case of metastatic prostate carcinoma in a 65-year-old Indian man with the unusual phenomenon of monoclonal band in gamma globulin region without evidence of bone marrow plasmacytosis.
CONCLUSIONS
Monoclonal gammopathy in solid tumor has seldom been reported. This case report highlights the rare association of monoclonal gammopathy with malignant prostatic carcinoma. Therefore, while investigating a case such as this, in an elderly male patient, we should always keep a lookout for any solid tumor foci after excluding multiple myeloma.
背景
单克隆丙种球蛋白病通常与浆细胞发育异常相关。然而，前列腺癌中无骨髓浆细胞增多的单克隆丙种球蛋白病鲜有报道。这两种情况之间的关联尚未明确确立。
病例报告
我们报告一例65岁印度男性转移性前列腺癌病例，该患者出现γ球蛋白区域单克隆条带这一不寻常现象，且无骨髓浆细胞增多的证据。
结论
实体瘤中的单克隆丙种球蛋白病鲜有报道。本病例报告突出了单克隆丙种球蛋白病与前列腺癌的罕见关联。因此，在调查此类老年男性患者病例时，排除多发性骨髓瘤后，我们应始终留意是否存在任何实体瘤病灶。
Zotero 插件