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年轻人的身体活动、久坐行为与长期心血管风险:前瞻性研究方法的综述与讨论

Physical activity, sedentary behavior, and long-term cardiovascular risk in young people: A review and discussion of methodology in prospective studies.

作者信息

Tarp Jakob, Brønd Jan Christian, Andersen Lars Bo, Møller Niels Christian, Froberg Karsten, Grøntved Anders

机构信息

Research Unit for Exercise Epidemiology, Centre of Research in Childhood Health, Department of Sport Science and Clinical Biomechanics, University of Southern Denmark, Campusvej 55, Odense 5230, Denmark.

Department of Sports Medicine, Norwegian School of Sport Sciences, Sognsveien 220, Oslo 0806, Norway.

出版信息

J Sport Health Sci. 2016 Jun;5(2):145-150. doi: 10.1016/j.jshs.2016.03.004. Epub 2016 Apr 1.

DOI:10.1016/j.jshs.2016.03.004
PMID:30356550
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6188740/
Abstract

The long-term effects of physical activity (PA) or sedentary behavior on cardiovascular health in young people are not well understood. In this study, we use a narrative format to review the evidence for a prospective association with adiposity and other well-established biological cardiovascular risk factors in healthy young people, considering only studies with at least 2 years of follow-up. PA appears to elicit a long-term beneficial effect on adiposity and particularly markers of cardiovascular health. With adiposity, however, a few studies also reported that higher levels of PA were associated with higher levels of adiposity. Time spent sedentary does not appear to be related to adiposity or markers of cardiovascular health independent of PA. We then discuss the uncertainties in the underlying causal chain and consider a number of alternative modeling strategies, which could improve our understanding of the relationship in future studies. Finally, we consider the current methodology for assessing PA and sedentary time.

摘要

体育活动(PA)或久坐行为对年轻人心血管健康的长期影响尚未得到充分了解。在本研究中,我们采用叙述形式回顾了健康年轻人中PA与肥胖及其他公认的心血管生物风险因素之间前瞻性关联的证据,仅考虑随访至少2年的研究。PA似乎对肥胖尤其是心血管健康标志物产生长期有益影响。然而,关于肥胖,一些研究也报告称较高水平的PA与较高水平的肥胖有关。久坐时间与肥胖或独立于PA的心血管健康标志物似乎无关。然后,我们讨论了潜在因果链中的不确定性,并考虑了一些替代建模策略,这些策略可能会在未来研究中增进我们对这种关系的理解。最后,我们考虑了当前评估PA和久坐时间的方法。

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