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精神分裂症中的情绪调节:一项通过脑电图和光学成像(功能近红外光谱)评估的初步临床干预。

Emotion Regulation in Schizophrenia: A Pilot Clinical Intervention as Assessed by EEG and Optical Imaging (Functional Near-Infrared Spectroscopy).

作者信息

Balconi Michela, Frezza Alessandra, Vanutelli Maria Elide

机构信息

Department of Psychology, Catholic University of Milan, Milan, Italy.

Research Unit in Affective and Social Neuroscience, Catholic University of Milan, Milan, Italy.

出版信息

Front Hum Neurosci. 2018 Oct 9;12:395. doi: 10.3389/fnhum.2018.00395. eCollection 2018.

DOI:10.3389/fnhum.2018.00395
PMID:30356708
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6189325/
Abstract

Previous research on Schizophrenia (S) revealed anomalies in brain responsiveness during emotion processing, as shown by neuroimaging and electroencephalography (EEG) measures. Nonetheless preserved capacities to explicitly evaluate the emotional significance of affective stimuli in term of valence have been found. The present study applied functional Near-Infrared Spectroscopy (fNIRS) and EEG to explore the spatial and temporal expressions of emotion processing in the brain before (T0) and after (T2) an emotional Neurofeedback (NF) training of patients, assigned to the control or the experimental group. Explicit measures revealed correct identifications of stimuli emotional valence before (T0) and after (T2) the treatment, while implicit measures (EEG and fNIRS) showed a modulation and increased competencies only after the NF (T2), with more balanced prefrontal activity.

摘要

先前对精神分裂症(S)的研究表明,通过神经影像学和脑电图(EEG)测量发现,在情绪处理过程中大脑反应存在异常。尽管如此,研究发现患者在明确评估情感刺激在效价方面的情感意义时仍具备一定能力。本研究应用功能近红外光谱(fNIRS)和脑电图(EEG)来探索,在将患者分为对照组或实验组进行情绪神经反馈(NF)训练之前(T0)和之后(T2),大脑中情绪处理的空间和时间表达。明确测量结果显示,治疗前(T0)和治疗后(T2)对刺激的情感效价都能正确识别,而隐式测量(EEG和fNIRS)仅在神经反馈训练后(T2)显示出调节作用和能力增强,前额叶活动更加平衡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8187/6189325/297441d4a3e5/fnhum-12-00395-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8187/6189325/297441d4a3e5/fnhum-12-00395-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8187/6189325/297441d4a3e5/fnhum-12-00395-g0001.jpg

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本文引用的文献

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Asian J Psychiatr. 2018 Apr;34:12-13. doi: 10.1016/j.ajp.2018.03.018. Epub 2018 Mar 13.
2
Event-related potentials (ERPs) and hemodynamic (functional near-infrared spectroscopy, fNIRS) as measures of schizophrenia deficits in emotional behavior.事件相关电位(ERPs)和血流动力学(功能近红外光谱,fNIRS)作为精神分裂症情绪行为缺陷的测量指标。
Front Psychol. 2015 Nov 3;6:1686. doi: 10.3389/fpsyg.2015.01686. eCollection 2015.
3
A Systematic Review of the Effects of EEG Neurofeedback on Patients with Schizophrenia.
脑电图神经反馈对精神分裂症患者影响的系统评价
J Pers Med. 2024 Jul 18;14(7):763. doi: 10.3390/jpm14070763.
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Probing fMRI brain connectivity and activity changes during emotion regulation by EEG neurofeedback.通过脑电图神经反馈探究功能磁共振成像(fMRI)大脑连接性和情绪调节过程中的活动变化。
Front Hum Neurosci. 2023 Jan 6;16:988890. doi: 10.3389/fnhum.2022.988890. eCollection 2022.
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A Systematic Review of the Potential Use of Neurofeedback in Patients With Schizophrenia.对精神分裂症患者使用神经反馈潜在用途的系统评价
Schizophr Bull Open. 2020 Jan;1(1):sgaa005. doi: 10.1093/schizbullopen/sgaa005. Epub 2020 Mar 2.
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