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结节病外周血T淋巴细胞亚群的特征分析

Characterization of peripheral blood T lymphocyte subsets in pulmonary sarcoidosis.

作者信息

Powell S, Eisenberg H, Siegal J, Perla E N

出版信息

Sarcoidosis. 1987 Mar;4(1):28-32.

PMID:3035675
Abstract

The peripheral blood of sarcoidosis patients has been shown to have abnormalities in the T Lymphocyte subsets. There is a consistent reduction in the helper/suppressor T Lymphocyte ratio caused by an increase in suppressor cell percentage as determined by monoclonal antibodies. These findings suggest that the peripheral blood T Lymphocyte subsets may be a useful adjunct for determining the underlying immunological cellular dysfunction in sarcoidosis patients.

摘要

结节病患者的外周血已显示出T淋巴细胞亚群异常。通过单克隆抗体测定,抑制细胞百分比增加导致辅助/抑制性T淋巴细胞比率持续降低。这些发现表明,外周血T淋巴细胞亚群可能是确定结节病患者潜在免疫细胞功能障碍的有用辅助手段。

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1
Characterization of peripheral blood T lymphocyte subsets in pulmonary sarcoidosis.结节病外周血T淋巴细胞亚群的特征分析
Sarcoidosis. 1987 Mar;4(1):28-32.
2
T-lymphocyte subsets in peripheral blood and lung lavage in idiopathic pulmonary fibrosis and sarcoidosis: analysis by monoclonal antibodies and flow cytometry.特发性肺纤维化和结节病患者外周血及肺灌洗中的T淋巴细胞亚群:单克隆抗体及流式细胞术分析
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Ann N Y Acad Sci. 1986;465:418-26. doi: 10.1111/j.1749-6632.1986.tb18518.x.
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[Bronchoalveolar lavage in patients with sarcoidosis--methodologic aspects of the collection, immunologic characterization of lymphocytes and studies of immunoglobulin content].[结节病患者的支气管肺泡灌洗——采集的方法学方面、淋巴细胞的免疫学特征及免疫球蛋白含量研究]
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Pulmonary sarcoidosis: excess of helper T lymphocytes and T cell subset imbalance at sites of disease activity.肺结节病:疾病活动部位辅助性T淋巴细胞增多及T细胞亚群失衡。
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Studies of peripheral blood monocytes in pulmonary sarcoidosis.肺结节病外周血单核细胞的研究。
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Blood helper/suppressor lymphocyte ratio in sarcoidosis.结节病中辅助/抑制性淋巴细胞比例
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Nihon Kyobu Shikkan Gakkai Zasshi. 1986 Mar;24(3):218-29.