Carl W, Herrera L
Semin Surg Oncol. 1987;3(2):77-83. doi: 10.1002/ssu.2980030206.
Dental and bone abnormalities of the maxilla and mandible are present in approximately 80% of patients with familial polyposis coli. The dental abnormalities include impacted teeth (other than third molars), supernumerary teeth, congenitally missing teeth, fused roots of first and second molars, and unusually long and tapered roots of posterior teeth. The bone lesions consist mostly of osteomas, either isolated or in clusters, in the maxilla and mandible or of exostoses with lateral and/or lingual extensions. Since dental and bone abnormalities are already present early in life there is a strong suggestion that they may be used as diagnostic features in the recognition of familial polyposis coli.
在大约80%的家族性结肠息肉病患者中存在上颌骨和下颌骨的牙齿及骨骼异常。牙齿异常包括阻生牙（第三磨牙除外）、多生牙、先天性缺牙、第一和第二磨牙的融合根以及后牙异常长且呈锥形的牙根。骨病变主要由上颌骨和下颌骨中的孤立性或成簇的骨瘤组成，或为由侧向和/或舌侧延伸的外生骨疣组成。由于牙齿和骨骼异常在生命早期就已出现，因此强烈提示它们可作为识别家族性结肠息肉病的诊断特征。
