Shahnazi Anahita, Badurdeen Dilhana, Laiyemo Adeyinka O, Nouraie Mehdi, Brim Hassan, Wessly Priscilla, Geramfard Sahar, Afsari Ali, Page Niel, Ashktorab Hassan
Department of Medicine, Howard University Hospital, Washington DC, USA.
Department of Medicine & Cancer Center, Howard University College of Medicine, Washington DC, USA.
Cureus. 2018 Aug 20;10(8):e3160. doi: 10.7759/cureus.3160.
Objective Obesity is one of the risk factors for pancreatic cancer and a prognostic factor for acute-chronic pancreatitis. Aim To explore the relationship and association between obesity and pancreatic cysts over a 25-year period in African American patients. Methods We reviewed the medical records of 207 patients diagnosed with pancreatic cysts via radiology and pathology data from January 1988 to December 2012. A control group was selected from a separate group of healthy patients without a history of pancreatic disease. The patients were evaluated in five groups according to the last 20 years of diagnosis in five-year intervals. Results Most patients with pancreatic cyst (73%) were overweight (defined as a body mass index (BMI) ≥ 25), and 53% had a history of chronic pancreatitis compared to patients in the control group. There was a significant difference between the two groups; 79% of patients group were overweight (BMI ≥ 25) vs. 66% in control group (p = 0.02). The incidence of obese and overweight patients was significant (85%) during the 2008 to 2012 interval for the test group (p = 0.009). Conclusion Given the increasing proportion of obese pancreatic cyst patients in recent decades compared to the proportion noted in the 1990s, obesity plays a large role in the formation of pancreatic cysts.
目的 肥胖是胰腺癌的危险因素之一，也是急慢性胰腺炎的预后因素。目的 探讨非裔美国患者在25年期间肥胖与胰腺囊肿之间的关系及关联。方法 我们回顾了1988年1月至2012年12月期间通过放射学和病理学数据诊断为胰腺囊肿的207例患者的病历。对照组从另一组无胰腺疾病史的健康患者中选取。根据诊断的最后20年，以五年为间隔将患者分为五组进行评估。结果 与对照组患者相比，大多数胰腺囊肿患者（73%）超重（定义为体重指数（BMI）≥25），53%有慢性胰腺炎病史。两组之间存在显著差异；患者组79%超重（BMI≥25），而对照组为66%（p = 0.02）。在2008年至2012年期间，试验组肥胖和超重患者的发生率显著（85%）（p = 0.009）。结论 与20世纪90年代记录的比例相比，近几十年来肥胖胰腺囊肿患者的比例不断增加，肥胖在胰腺囊肿的形成中起很大作用。
