马抗血清识别的马疱疹病毒1型（EHV 1）蛋白及其促进抗体依赖性细胞介导的细胞毒性的能力。
The proteins of equid herpesvirus 1 (EHV 1) recognised by equine antisera and their ability to promote antibody-dependent cell-mediated cytotoxicity.
作者信息
Bridges C G, Edington N
出版信息
Tierarztl Prax Suppl. 1987;2:47-9.
PMID:3035747
Abstract
Equine sera were used to immunoprecipitate radiolabelled virus-infected cell proteins; subsequent resolution with polyacrylamide gel electrophoresis identified the EHV-1 polypeptides VP 2, 10a, 11, 13, 14, 15, 16, 20, 21 and 23a. The humoral support of ADCC by these sera was examined in vitro. Cytotoxicity could be demonstrated against both subtypes irrespective of the immunising isolate. The implications of these results are discussed.
摘要
马血清用于免疫沉淀放射性标记的病毒感染细胞蛋白；随后通过聚丙烯酰胺凝胶电泳进行分离，鉴定出了EHV - 1多肽VP 2、10a、11、13、14、15、16、20、21和23a。体外检测了这些血清对ADCC的体液支持作用。无论免疫分离株如何，对两种亚型均能证明有细胞毒性。讨论了这些结果的意义。
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