Pan Sheng-Wu, Wang Chang, Zhang Xin, Zhang Li, Yan Qi-Qi, Zhao Cai-Juan, Chang Cheng, Luan Xiao-Dong
Department of Gastroenterology, People's Liberation Army 264 Hospital, No. 30, Qiaodong Street, Yingze District, Taiyuan, 030000, Shanxi Province, China.
Public Relations Branch,Taiyuan Red Cross Blood Center, Taiyuan, 030022, China.
BMC Gastroenterol. 2018 Oct 25;18(1):154. doi: 10.1186/s12876-018-0885-9.
The involvement of granulomatosis with polyangiitis is less frequent in the intestine.
We present a case of Wegener's granulomatosis with unusual endoscopic appearance, involvement in a young man's gastrointestinal tract. A 45-year-old man was diagnosed with Wegener's granulomatosis 11 years ago, and relapsed with abdominal pain and melena. A colonoscopy was performed, and the appearance of mucosal lesions with an unusual annular black membrane was observed. A black ring-shaped membranous tissue adhered to the surface of the colon wall, which could be traversed by an endoscopic forepart.
Biopsy of the black membrane revealed degenerative colonic mucosal tissues, while deep colonic biopsy revealed inflammatory granulation tissues. This has not been reported in previous documents.
肉芽肿性多血管炎累及肠道的情况较少见。
我们报告一例韦格纳肉芽肿病,其内镜表现异常,累及一名年轻男性的胃肠道。一名45岁男性11年前被诊断为韦格纳肉芽肿病,此次因腹痛和黑便复发。进行了结肠镜检查,观察到黏膜病变呈现异常的环形黑膜外观。一个黑色环形膜状组织附着在结肠壁表面,内镜前端可以穿过该组织。
黑膜活检显示为退行性结肠黏膜组织,而结肠深部活检显示为炎性肉芽组织。此前文献未见相关报道。