Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Neuron. 2018 Oct 24;100(2):453-462. doi: 10.1016/j.neuron.2018.10.017.
Major changes are underway in the field of perceptual decision-making. Single-neuron studies have given way to population recordings with identified cell types, traditional analyses have been extended to accommodate these large and diverse collections of neurons, and novel methods of neural disruption have provided insights about causal circuits. Further, the field has expanded to include multiple new species: rodents and invertebrates, for example, have been instrumental in demonstrating the importance of internal state on neural responses. Finally, a renewed interest in ethological stimuli prompted development of new behaviors, frequently analyzed by new, automated movement tracking methods. Taken together, these advances constitute a seismic shift in both our approach and understanding of how incoming sensory signals are used to guide decisions.
在感知决策领域正在发生重大变化。单细胞研究已经让位于具有鉴定细胞类型的群体记录,传统的分析方法已经扩展到适应这些大量和多样化的神经元集合,以及神经干扰的新方法提供了关于因果回路的见解。此外,该领域已经扩展到包括多个新物种:例如,啮齿动物和无脊椎动物在证明内部状态对神经反应的重要性方面发挥了重要作用。最后,对行为学刺激的重新关注促使新行为的发展,这些行为通常通过新的、自动化的运动跟踪方法进行分析。总的来说,这些进展构成了我们对传入感觉信号如何用于指导决策的方法和理解的重大转变。