Evrard I, Gruyer X, Desse P, Francois A, Marie J P, Dehesdin D, Andrieu-Guitrancourt J
CHU Charles Nicolle, Rouen.
Ann Otolaryngol Chir Cervicofac. 1998 May;115(2):85-8.
We report an unusual case of spheno-ethmoidal rhinoscleroma. This chronic granulomatous disease occurs sporadically in Western Europe. Culture is necessary for diagnosis showing the causative organism of rhinoscleroma, Klebsiella rhinoscleromatis. Immunocytochemistry is used in any suspicious case with a negative culture. Antibiotics are the mainstay of therapy for several weeks, using ciprofloxacine or rifampicin, until the nasal biopsies demonstrated no Klebsiella organism.
我们报告了一例罕见的蝶筛窦鼻硬结病病例。这种慢性肉芽肿性疾病在西欧偶有发生。诊断需要进行培养以显示鼻硬结病的病原体——鼻硬结克雷伯菌。对于培养结果为阴性的任何可疑病例，需采用免疫细胞化学方法。治疗主要依靠使用环丙沙星或利福平的抗生素持续数周，直到鼻活检显示无克雷伯菌属微生物。
