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谁想换药?评估患者对新型抗逆转录病毒疗法的兴趣。

Who Wants to Switch? Gauging Patient Interest in Novel Antiretroviral Therapies.

作者信息

Derrick Caroline B, Ostermann Jan, Weissman Sharon B, Hobbie Amy, Alshareef Noor, Weinhold Andrew, Yelverton Valerie, Thielman Nathan M

机构信息

Department of Medicine, School of Medicine, University of South Carolina, Columbia, South Carolina.

Department of Health Services Policy and Management, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina.

出版信息

Open Forum Infect Dis. 2018 Oct 22;5(10):ofy247. doi: 10.1093/ofid/ofy247. eCollection 2018 Oct.

Abstract

Study participants were asked about their interest in switching to novel drug delivery systems that reduce the dosing frequency of antiretroviral regimens. Across a diverse, treatment-experienced cohort, we describe greatest interest in switching to an oral regimen taken once weekly, followed by injections taken every other month and twice-annual implants.

摘要

研究参与者被问及他们对改用新型药物递送系统的兴趣,这些系统可减少抗逆转录病毒疗法的给药频率。在一个多样化的、有治疗经验的队列中,我们发现对改用每周服用一次的口服疗法兴趣最大,其次是每两个月注射一次和每年植入两次。

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