Microbial Resource and Big Data Center, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
Nucleic Acids Res. 2019 Jan 8;47(D1):D637-D648. doi: 10.1093/nar/gky1008.
Meta-omics approaches have been increasingly used to study the structure and function of the microbial communities. A variety of large-scale collaborative projects are being conducted to encompass samples from diverse environments and habitats. This change has resulted in enormous demands for long-term data maintenance and capacity for data analysis. The Global Catalogue of Metagenomics (gcMeta) is a part of the 'Chinese Academy of Sciences Initiative of Microbiome (CAS-CMI)', which focuses on studying the human and environmental microbiome, establishing depositories of samples, strains and data, as well as promoting international collaboration. To accommodate and rationally organize massive datasets derived from several thousands of human and environmental microbiome samples, gcMeta features a database management system for archiving and publishing data in a standardized way. Another main feature is the integration of more than ninety web-based data analysis tools and workflows through a Docker platform which enables data analysis by using various operating systems. This platform has been rapidly expanding, and now hosts data from the CAS-CMI and a number of other ongoing research projects. In conclusion, this platform presents a powerful and user-friendly service to support worldwide collaborative efforts in the field of meta-omics research. This platform is freely accessible at https://gcmeta.wdcm.org/.
元组学方法已被越来越多地用于研究微生物群落的结构和功能。各种大型合作项目正在进行中，涵盖了来自不同环境和栖息地的样本。这种变化导致对长期数据维护和数据分析能力的巨大需求。元基因组全球目录（gcMeta）是“中国科学院微生物组计划（CAS-CMI）”的一部分，该计划专注于研究人类和环境微生物组，建立样本、菌株和数据储存库，并促进国际合作。为了容纳和合理组织来自数千个人类和环境微生物组样本的大量数据集，gcMeta 具有一个数据库管理系统，用于以标准化方式归档和发布数据。另一个主要特点是通过 Docker 平台集成了 90 多个基于网络的数据分析工具和工作流程，该平台允许使用各种操作系统进行数据分析。该平台正在迅速扩展，现在托管来自 CAS-CMI 和其他一些正在进行的研究项目的数据。总之，该平台为元组学研究领域的全球合作提供了强大而用户友好的服务。该平台可在 https://gcmeta.wdcm.org/ 免费访问。
