Department of Dermatology and Laboratory Medicine, Gachon University Gil Medical Center, Incheon, South Korea.
Department of Internal Medicine, Inje University Sanggye Paik Hospital, Inje University College of Medicine, Seoul, South Korea.
Dermatol Ther. 2019 Jan;32(1):e12775. doi: 10.1111/dth.12775. Epub 2018 Nov 19.
Nocardiosis is a rare localized or systemic suppurative disease caused by the actinomycete Nocardia species. The respiratory tract is the most common site of infection, but primary cutaneous nocardiosis can also be induced by direct inoculation. Nocardiosis is usually reported in immunocompromised patients, such as those with human immunodeficiency virus (HIV) infection, chronic obstructive pulmonary disease, autoimmune diseases, cancer, or in those who have had organ transplantation or corticosteroid administration. However, it can also affect individuals with no serious underlying condition. We reported two cases of primary cutaneous nocardiosis in immunocompetent patients after intralesional injection of steroid.
奴卡菌病是一种罕见的局部或全身化脓性疾病，由放线菌属奴卡菌引起。呼吸道是最常见的感染部位，但原发性皮肤奴卡菌病也可由直接接种引起。奴卡菌病通常发生于免疫功能低下的患者，如人类免疫缺陷病毒（HIV）感染者、慢性阻塞性肺疾病、自身免疫性疾病、癌症患者，或接受过器官移植或皮质类固醇治疗的患者。然而，它也可能影响没有严重潜在疾病的个体。我们报告了两例免疫功能正常的患者在皮损内注射类固醇后发生原发性皮肤奴卡菌病的病例。
