Kenya Medical Research Institute/Wellcome Trust Research Programme, Nairobi, Kenya.
Department of Paediatrics and Child Health, University of Nairobi, Nairobi, Kenya.
Trop Med Int Health. 2019 Jan;24(1):73-80. doi: 10.1111/tmi.13176. Epub 2018 Nov 11.
WHO recommends optimisation of available interventions to reduce deaths of under-five children with diarrhoea and dehydration (DD). Clinical networks may help improve practice across many hospitals but experience with such networks is scarce. We describe magnitude and patterns of changes in processes of care for children with DD over the first 3 years of a clinical network.
Observational study involving children aged 2-59 months with DD admitted to 13 hospitals participating in the clinical network. Processes of individual patient care including agreement of assessment, diagnosis and treatment according to WHO guidelines were combined using the composite Paediatric Admission Quality of Care (PAQC) score (range 0-6).
Data from 7657 children were analysed and improvements in PAQC scores were observed. Predicted mean PAQC score for all the hospitals at enrolment was 59.8% (95% CI: 54.7, 64.9) but showed a wide variation (variance 10.7%, 95% CI: 5.8, 19.6). Overall mean PAQC score increased by 13.8% (95% CI: 8.7-18.9, SD between hospitals: ±8.2) in the first 12 months, with an average 0.9% (95% CI: 0.3-1.5, SD ± 1.0) increase per month and plateaued thereafter, and changes were similar in two groups of hospitals joining the network at different times.
Adherence to guidelines for children admitted with DD can be improved through participation in a clinical network but improvement is limited, not uniform for all aspects of care and contexts and occurs early. Future research should address these issues.
世界卫生组织建议优化现有干预措施,以减少患有腹泻和脱水(DD)的五岁以下儿童的死亡。临床网络可能有助于改善许多医院的实践,但此类网络的经验很少。我们描述了临床网络建立的头 3 年中,儿童腹泻脱水患者的治疗过程的变化幅度和模式。
这是一项观察性研究,涉及参与临床网络的 13 家医院收治的 2-59 月龄患有 DD 的儿童。将根据世卫组织指南对个体患者进行评估、诊断和治疗的情况纳入综合儿科入院护理质量(PAQC)评分(0-6 分),以综合评估患者护理过程。
共分析了 7657 名儿童的数据,观察到 PAQC 评分有所提高。所有医院在入组时的预测平均 PAQC 评分为 59.8%(95%CI:54.7,64.9),但差异较大(方差 10.7%,95%CI:5.8,19.6)。在最初的 12 个月中,总体平均 PAQC 评分增加了 13.8%(95%CI:8.7-18.9,医院间标准差:±8.2),平均每月增加 0.9%(95%CI:0.3-1.5,SD±1.0),此后趋于平稳,且两组在不同时间加入网络的医院的变化情况相似。
通过参与临床网络,可提高儿童腹泻脱水入院患者对指南的依从性,但改善程度有限,并非所有护理方面和所有情况下都统一,且发生于早期。未来的研究应解决这些问题。