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结痂性(挪威型)疥疮:医源性免疫抑制导致的九个月病程

Crusted (Norwegian) Scabies: Nine-Month Course With Iatrogenic Immunosuppression.

作者信息

Tolkachjov Stanislav N, Davis Mark D P, Yiannias James A

出版信息

J Drugs Dermatol. 2018 Oct 1;17(10):1131-1133.

Abstract

Crusted scabies (CS) is a highly infectious hyperinfestation variant of scabies with up to millions of Sarcoptes scabiei mites present on the skin surface. Diagnostic clues include intense itching and thick crusting especially on the face, groin, and buttocks, although variable presentations may mimic other dermatoses. CS has been associated with immunosuppression including the human immunodeficiency virus (HIV) and lymphoreticular malignancies.1-3 A long latency period from symptom onset to diagnosis and appropriate treatment is often reported. Clinical suspicion is required to obtain a mineral oil preparation or biopsy. We report a patient treated for eczema with 9 months of progressive immunosuppression who was found to have crusted scabies. J Drugs Dermatol. 2018;17(10):1131-1133.

摘要

结痂性疥疮(CS)是疥疮的一种具有高度传染性的超感染变体,皮肤表面存在多达数百万只疥螨。诊断线索包括剧烈瘙痒和厚痂皮,尤其是在面部、腹股沟和臀部,尽管其表现形式多样,可能会与其他皮肤病相混淆。CS与免疫抑制有关,包括人类免疫缺陷病毒(HIV)和淋巴网状恶性肿瘤。1-3 经常有报道称,从症状出现到诊断及适当治疗存在较长的潜伏期。需要临床怀疑才能进行矿物油涂片或活检。我们报告了一名因湿疹接受治疗9个月且进行性免疫抑制的患者,该患者被发现患有结痂性疥疮。《皮肤药物学杂志》。2018年;17(10):1131-1133。

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