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结痂性角化过度型疥疮:病例报告

Crusted Hyperkeratotic Scabies: A Case Report.

作者信息

Meraz Soto Juan Marcos, Alvarado Motte Ramiro Aleksander, Ramírez Carrillo Paola, Meraz Soto Alan Axel, Bayón Villaseñor Valeria, Cheirif Wolosky Orly

机构信息

Dermatology, Xochicalco University, Tijuana, MEX.

Dermatology, Autonomous University of Baja California, Tijuana, MEX.

出版信息

Cureus. 2023 Feb 1;15(2):e34520. doi: 10.7759/cureus.34520. eCollection 2023 Feb.

DOI:10.7759/cureus.34520
PMID:36879685
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9984309/
Abstract

Crusted scabies is a rare form of classic scabies characterized by severe symptoms, mainly observed in immunosuppressed patients. This disease has been associated with a variety of health problems, such as delayed diagnosis, infection risk, and high mortality, mainly from sepsis. We report the case of a patient with hyperkeratotic scabies in the context of immunosuppression associated with malnutrition and the use of topical corticosteroids. Ivermectin is critical for successfully treating crusted scabies. However, a higher cure rate has been reported with the combination of oral ivermectin and topical permethrin. In our study, we chose to use a plan suitable for grade two scabies, resulting in a subtotal regression of the lesions. Crusted scabies is a highly contagious parasitic cutaneous disease, and there are few reports in the national and international literature. It is necessary to suspect this presentation form in order to establish a timely diagnosis and detect and treat associated comorbidities.

摘要

结痂性疥疮是经典疥疮的一种罕见形式,其特征为症状严重,主要见于免疫抑制患者。这种疾病与多种健康问题相关,如诊断延迟、感染风险以及主要由败血症导致的高死亡率。我们报告了一例在免疫抑制背景下合并营养不良及使用外用糖皮质激素的角化过度型疥疮患者。伊维菌素对于成功治疗结痂性疥疮至关重要。然而,口服伊维菌素与外用氯菊酯联合使用的治愈率更高。在我们的研究中,我们选择了适用于二级疥疮的方案,使皮损基本消退。结痂性疥疮是一种具有高度传染性的寄生性皮肤病,国内外文献报道较少。有必要怀疑这种表现形式以便及时诊断并检测和治疗相关合并症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47eb/9984309/011db8ff8b8c/cureus-0015-00000034520-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47eb/9984309/4337ebd5d80b/cureus-0015-00000034520-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47eb/9984309/c99ccdbef5c6/cureus-0015-00000034520-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47eb/9984309/011db8ff8b8c/cureus-0015-00000034520-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47eb/9984309/4337ebd5d80b/cureus-0015-00000034520-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47eb/9984309/c99ccdbef5c6/cureus-0015-00000034520-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47eb/9984309/011db8ff8b8c/cureus-0015-00000034520-i03.jpg

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Infect Dis Rep. 2022 Jun 16;14(3):479-491. doi: 10.3390/idr14030051.
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Scabies: update on treatment and efforts for prevention and control in highly endemic settings.疥疮:高流行地区治疗以及预防和控制工作的最新进展。
J Infect Dev Ctries. 2022 Feb 28;16(2):244-251. doi: 10.3855/jidc.15222.
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Clinical diagnosis and treatment of scabies, a neglected tropical disease.临床诊断与治疗疥疮,一种被忽视的热带病。
AME Case Rep. 2024 Feb 21;8:30. doi: 10.21037/acr-23-125. eCollection 2024.
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Active case detection methods for crusted scabies and leprosy: A systematic review.针对结痂性疥疮和麻风病的主动病例检测方法:系统评价。
PLoS Negl Trop Dis. 2021 Jul 23;15(7):e0009577. doi: 10.1371/journal.pntd.0009577. eCollection 2021 Jul.
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Scabies: Diagnostic and Therapeutic Update.疥疮:诊断与治疗的最新进展。
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Ectoparasites: Scabies.体外寄生虫:疥疮。
J Am Acad Dermatol. 2020 Mar;82(3):533-548. doi: 10.1016/j.jaad.2019.05.109. Epub 2019 Jul 13.
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A systematic review of scabies transmission models and data to evaluate the cost-effectiveness of scabies interventions.系统评价疥疮传播模型和数据,以评估疥疮干预措施的成本效益。
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