The Graduate Center, City University of New York, United States; Queens College, City University of New York, United States.
The Graduate Center, City University of New York, United States; Queens College, City University of New York, United States.
J Affect Disord. 2019 Feb 15;245:28-37. doi: 10.1016/j.jad.2018.10.109. Epub 2018 Oct 17.
Computerized cognitive training (CCT) has previously improved cognition and mood in people with depression. Existing research has not determined if the benefits following CCT are specific to the content of CCT or are a function of participation in an engaging activity. In this double-blind randomized controlled trial, we tested whether executive functioning and processing speed (EF/PS)-focused CCT could outperform verbal ability-focused CCT.
46 young adults with at least mild depressive symptoms (HDRS ≥ 10) were recruited from the community and randomized to either EF/PS CCT or verbal ability CCT. Participants trained on their mobile device 5 days per week for 8 weeks. Depressive severity, everyday functioning, and cognition were evaluating pre and post-training.
The EF/PS group had greater gains in executive functioning and processing speed than the verbal group. There were no differences between groups in mood or everyday functioning improvement, though the EF/PS obtained equivalent improvement with half the training time. Both groups saw significant improvements in self and clinician-rated depressive severity, everyday functioning, and cognition.
There was no waitlist control condition and the sample consisted of individuals with mild depressive symptoms and not diagnosed major depressive disorder.
CCT is associated with improved mood, cognition, and everyday functioning, though the type of CCT content does not differentially impact depressive symptom change. EF/PS focused CCT has greater impact on processing speed and executive functioning and leads to equivalent mood/everyday functioning gains as verbal-focused CCT more efficiently. Common factors remain plausible drivers of CCT's therapeutic effects.
计算机认知训练(CCT)此前已改善了抑郁症患者的认知和情绪。现有研究尚未确定 CCT 后带来的益处是否是 CCT 内容的特异性,还是参与有趣活动的功能。在这项双盲随机对照试验中,我们测试了以执行功能和处理速度(EF/PS)为重点的 CCT 是否优于以语言能力为重点的 CCT。
从社区招募了 46 名至少有轻度抑郁症状(HDRS≥10)的年轻人,并将他们随机分为 EF/PS CCT 组或语言能力 CCT 组。参与者在移动设备上每周训练 5 天,持续 8 周。在训练前后评估抑郁严重程度、日常功能和认知。
EF/PS 组在执行功能和处理速度方面的增益大于语言组。两组在情绪或日常功能改善方面没有差异,尽管 EF/PS 组只用了一半的训练时间就获得了同等的改善。两组患者的自我和临床医生评定的抑郁严重程度、日常功能和认知均有显著改善。
没有候补控制条件,样本由轻度抑郁症状且未诊断为重度抑郁症的个体组成。
CCT 与改善情绪、认知和日常功能有关,但 CCT 内容的类型并不会对抑郁症状的变化产生不同影响。以执行功能和处理速度为重点的 CCT 对处理速度和执行功能的影响更大,并且与以语言为重点的 CCT 一样,能够更有效地获得同等的情绪/日常功能改善。共同因素仍然是 CCT 治疗效果的合理驱动因素。