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一名女性患者舌部促纤维增生性纤维瘤的罕见表现。

Uncommon presentation of desmoplastic fibroblastoma on the tongue of a female patient.

作者信息

Tokura Takaaki, Kobayashi Jun-Ichi, Okamoto Jun-Ya, Miyazaki Akihiro

机构信息

Department of Oral Surgery, Sapporo Medical University School of Medicine, Sapporo, Japan.

出版信息

BMJ Case Rep. 2018 Oct 27;2018:bcr-2018-226962. doi: 10.1136/bcr-2018-226962.

DOI:10.1136/bcr-2018-226962
PMID:30368477
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6214387/
Abstract

Desmoplastic fibroblastoma (DF) is a rare benign soft tissue with spindle-to-stellate-shaped fibroblasts and myofibroblasts embedded in a prominent collagenous background. DF, mainly affecting subcutaneous and muscle tissue, very rarely occurs in the oral cavity. Hitherto, only one case of DF on the tongue has been reported. Here, we report another case. A 66-year-old woman was referred to our hospital with a mass formation in the tongue. On examination, a well-circumscribed, elastic, soft tumour with normal surface mucosa, measuring 13×12 mm, was observed on the left dorsal surface of her tongue. MRI and ultrasonography confirmed the mass, and a benign tongue tumour was suspected. The tumour was surgically resected under general anaesthesia 1 month later, leading to the histopathological diagnosis of DF. She experienced an uneventful clinical recovery after surgery, with no recurrence noted for more than 1 year postoperatively.

摘要

促纤维增生性纤维瘤(DF)是一种罕见的良性软组织肿瘤,由梭形至星状的成纤维细胞和肌成纤维细胞嵌入显著的胶原背景中。DF主要累及皮下和肌肉组织,极少发生于口腔。迄今为止,仅报道过1例舌部DF。在此,我们报告另一例。一名66岁女性因舌部肿物被转诊至我院。检查发现,在其舌背左侧有一个边界清晰、质地坚韧、柔软的肿瘤,表面黏膜正常,大小为13×12毫米。磁共振成像(MRI)和超声检查证实了该肿物,怀疑为良性舌肿瘤。1个月后,在全身麻醉下对肿瘤进行了手术切除,术后病理诊断为DF。术后她临床恢复顺利,术后1年多未复发。

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本文引用的文献

1
Desmoplastic fibroblastoma (collagenous fibroma) in the oral cavity.口腔促结缔组织增生性纤维瘤(胶原纤维瘤)
J Indian Soc Pedod Prev Dent. 2014 Jul-Sep;32(3):238-41. doi: 10.4103/0970-4388.135834.
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Collagenous fibroma (desmoplastic fibroblastoma) of the oral cavity.口腔胶原纤维瘤(促结缔组织增生性纤维母细胞瘤)
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FOSL1 as a candidate target gene for 11q12 rearrangements in desmoplastic fibroblastoma.FOSL1 作为促纤维增生性纤维瘤中 11q12 重排的候选靶基因。
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Collagenous fibroma (desmoplastic fibroblastoma) of the palate: a case report.腭部胶原纤维瘤(促结缔组织增生性纤维母细胞瘤):一例报告
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