Center for Eco-friendly New Materials, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.
Division of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea.
World J Microbiol Biotechnol. 2018 Oct 28;34(11):163. doi: 10.1007/s11274-018-2546-0.
Aromatic polyketides are secondary metabolites widely found in bacteria, fungi, and plants, which are well-known for their diverse chemical structures and biological functions. The structural diversity of aromatic polyketides arises from a series of enzymatic modifications of the linear poly-β-ketone intermediates during biosynthesis. Their versatile bioactivities are exemplified by reports of their use as antibacterials, antifungals, antivirals, and antiparasitics. Despite many reports on the antimicrobial nature of aromatic polyketides, their potential use as plant disease control agents has still not been systematically explored and discussed. This review highlights examples of the use of aromatic polyketides as plant disease control agents and discusses their function and merits as agrochemicals.
芳香族聚酮类化合物是广泛存在于细菌、真菌和植物中的次生代谢产物，以其多样化的化学结构和生物功能而闻名。芳香族聚酮类化合物的结构多样性源于生物合成过程中线性聚β-酮中间产物的一系列酶促修饰。它们多样的生物活性表现在报道的作为抗菌剂、抗真菌剂、抗病毒剂和抗寄生虫剂的用途上。尽管有许多关于芳香族聚酮类化合物的抗菌性质的报道，但它们作为植物病害防治剂的潜在用途尚未得到系统的探索和讨论。本综述强调了芳香族聚酮类化合物作为植物病害防治剂的应用实例，并讨论了它们作为农用化学品的功能和优点。
