在磁共振成像过程中进行自适应和无线的电生理信号记录。
Adaptive and Wireless Recordings of Electrophysiological Signals During Concurrent Magnetic Resonance Imaging.
出版信息
IEEE Trans Biomed Eng. 2019 Jun;66(6):1649-1657. doi: 10.1109/TBME.2018.2877640. Epub 2018 Oct 23.
Strong electromagnetic fields that occur during functional magnetic resonance imaging (fMRI) presents a challenging environment for concurrent electrophysiological recordings. Here, we present a miniaturized, wireless platform-"MR-Link" (Multimodal Recording Link) that provides a hardware solution for simultaneous electrophysiological and fMRI signal acquisition. The device detects the changes in the electromagnetic field during fMRI to synchronize amplification and sampling of electrophysiological signals with minimal artifacts. It wirelessly transmits the recorded data at a frequency detectable by the MR-receiver coil. The transmitted data is readily separable from MRI in the frequency domain. To demonstrate its efficacy, we used this device to record electrocardiograms and somatosensory evoked potential during concurrent fMRI scans. The device minimized the fMRI-induced artifacts in electrophysiological data and wirelessly transmitted the data back to the receiver coil without compromising the fMRI signal quality. The device is compact (22 mm dia., 2 gms) and can be placed within the MRI bore to precisely synchronize with fMRI. Therefore, MR-Link offers an inexpensive system by eliminating the need for amplifiers with a high dynamic range, high-speed sampling, additional storage, or synchronization hardware for electrophysiological signal acquisition. It is expected to enable a broader range of applications of simultaneous fMRI and electrophysiology in animals and humans.
强电磁场在功能磁共振成像(fMRI)期间发生,为同时进行的电生理记录带来了挑战环境。在这里,我们提出了一种小型化、无线的平台——“MR-Link”(多模态记录链接),为同时获取电生理和 fMRI 信号提供了硬件解决方案。该设备检测 fMRI 期间电磁场的变化,以最小的伪影同步放大和采样电生理信号。它以可被 MR 接收器线圈检测到的频率无线传输记录的数据。传输的数据在频域中可与 MRI 轻松分离。为了证明其功效,我们在同时进行的 fMRI 扫描期间使用该设备记录心电图和体感诱发电位。该设备将 fMRI 引起的电生理数据伪影最小化,并将数据无线传输回接收器线圈,而不会影响 fMRI 信号质量。该设备体积小巧(直径 22 毫米,重 2 克),可放置在 MRI 孔内,与 fMRI 精确同步。因此,MR-Link 通过消除对高动态范围、高速采样、额外存储或电生理信号采集同步硬件的放大器的需求,提供了一种廉价的系统。它有望在动物和人类中更广泛地应用同时进行的 fMRI 和电生理学。
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