α-羟基肟醚的立体选择性还原：合成顺式-1,2-氨基醇的便捷途径。
STEREOSELECTIVE REDUCTION OF α-HYDROXY OXIME ETHERS: A CONVENIENT ROUTE TO CIS-1,2-AMINO ALCOHOLS.
作者信息
Ghosh Arun K, Mckee Sean P, Sanders Wilham M
机构信息
Department of Chemistry, Merck Sharp & Dohme Research Laboratories West Point, Pennsylvania 19486.
出版信息
Tetrahedron Lett. 1991 Feb 4;32(6):711-714. doi: 10.1016/S0040-4039(00)74864-7. Epub 2001 Mar 9.
Abstract
Reduction of cyclic α-hydroxyketoximes with borane provides an excellent, high yielding, regio- and stereoselective route to CIS-1, 2-amlnoalcohols.
摘要
用硼烷还原环状α-羟基酮肟为制备顺式-1,2-氨基醇提供了一条出色的、高产率的、区域和立体选择性的路线。
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