Division of Maricultural Organism Disease Control and Molecular Pathology, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, China.
Department of Microbiology, Oregon State University, Corvallis, OR 97331, USA.
Environ Microbiol. 2019 Feb;21(2):513-520. doi: 10.1111/1462-2920.14461. Epub 2018 Dec 3.
Trimethylamine (TMA) is common in marine environments. Although the presence of this compound in the oceans has been known for a long time, unlike the mammalian gastrointestinal tract, where TMA metabolism by microorganisms has been studied intensely, many questions remain unanswered about the microbial metabolism of marine TMA. This minireview summarizes what is currently known about the sources and fate of TMA in marine environments and the different pathways and enzymes involved in TMA metabolism in marine bacteria. This review also raises several questions about microbial TMA metabolism in the marine environments and proposes potential directions for future studies.
三甲胺（TMA）在海洋环境中很常见。尽管这种化合物在海洋中的存在已经被人们认识了很长时间，但与哺乳动物胃肠道中微生物强烈研究 TMA 代谢不同，关于海洋 TMA 的微生物代谢仍有许多问题尚未得到解答。这篇综述总结了目前已知的海洋环境中 TMA 的来源和归宿，以及海洋细菌中 TMA 代谢涉及的不同途径和酶。本文还提出了海洋环境中微生物 TMA 代谢的几个问题，并为未来的研究提出了潜在的方向。
